Chemical Constituents from Dried Aerial Parts of Eclipta prostrata

HAN Li-feng; ZHAO Jing; ZHANG Yi; KOJO Agyemang; LIU Er-wei; WANG Tao; HAN Li-feng; ZHAO Jing; ZHANG Yi; KOJO Agyemang; LIU Er-wei; WANG Tao

Archive > Volume 5 Issue 4 > 2013,5(4):313-316. DOI:10.1016/S1674-6384(13)60047-7 Prev Next

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Chemical Constituents from Dried Aerial Parts of Eclipta prostrata

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Abstract:

Objective To study the constituents in the dried aerial parts of Eclipta prostrata. Methods The constituents were isolated and purified by column chromatography and their structures were elucidated by spectroscopic methods (1D, 2D NMR, UV, IR, and HRESI-TOF-MS) and chemical analyses. Results Eight compounds were isolated and identified as 7-O-methylorobol-4′-O-β-D-glucopyranoside (1), 3′-hydroxybiochanin A (2), echinocystic acid 28-O-β-D-glucopyranoside (3), ecliptasaponin A (4), eclalbasaponin I (5), eclalbasaponin IV (6), echinocystic acid (7), and 3-oxo-16α-hydroxy-olean-12-en-28-oic acid (8). Conclusion Compound 1 is a new compound and compound 3 is obtained from this genus for the first time.

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Program for New Century Excellent Talents in University (NCET-10-0958), Important Drug Development Fund, Ministry of Science and Technology of China (2011ZX09307-002-01)

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