inner) of sugars and sapogenins (m/z 475 for protopanaxatriol; m/z 459 for protopanaxadiol), while the intact glycosyl portion could be characterized by characteristic Z0α+, Cnα+, and Cnβ+ (n = 2 or 3) obtained in the positive mode. Ultimately, a total of 30 saponins were characterized from XST. Compared with the roots of P. notoginseng, three malonyl-ginsenosides, ginsenoside Rd, and gyponoside XVII (or its isomer) were almost undetectable, and showed potential significance for their differentiation. Conclusion The established LC-MS profiling approach is powerful for the chemical analysis of P. notoginseng and its preparations such as XST."/>

醉酒后少妇被疯狂内射视频,一本色道久久综合一,在线天堂新版资源www在线下载,中文字幕乱人伦高清视频,中字幕视频在线永久在线观看免费

Archive > Volume 7 Issue 1 > 2015,7(1):54-61. DOI:10.1016/S1674-6384(15)60020-X Prev Next

Original articles

Chemical Analysis of Xueshuantong Lyophilized Powder by LC-MS Profiling

  • Article
  • Figures
  • Metrics
  • Preview PDF
  • Reference
  • Related
  • Cited by
  • Materials
    摘要:


    Abstract:
    Objective To elucidate the chemical components of Xueshuantong (XST) Lyophilized Powder and primarily disclose the chemical difference between XST and Panax notoginseng roots. Methods Liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MSn) was used to profile the saponins in XST and P. notoginseng. Structural elucidation was based on spectral analyses of negative and positive ESI-MS3 data, and the comparison of the retention behaviors. Results The optimized LC-MS profiling approach enabled resolution of major saponins. The negative mode ESI-MS3 fragmentation gave diagnostic information on the nature (neutral loss 162 Da for Glc, 146 Da for Rha, and 132 Da for a pentose) and sequence (priority: terminal > inner) of sugars and sapogenins (m/z 475 for protopanaxatriol; m/z 459 for protopanaxadiol), while the intact glycosyl portion could be characterized by characteristic Z0α+, Cnα+, and Cnβ+ (n = 2 or 3) obtained in the positive mode. Ultimately, a total of 30 saponins were characterized from XST. Compared with the roots of P. notoginseng, three malonyl-ginsenosides, ginsenoside Rd, and gyponoside XVII (or its isomer) were almost undetectable, and showed potential significance for their differentiation. Conclusion The established LC-MS profiling approach is powerful for the chemical analysis of P. notoginseng and its preparations such as XST.

    關(guān)鍵詞:


    Keywords:


    Project Supported:
    Twelfth Five-Year National Science & Technology Support Program (2012BA129B06)

    Clc Number:

WeChat

Mobile website