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Archive > Volume 11 Issue 2 > 2019,11(2):141-149. DOI:10.1016/j.chmed.2019.04.004 Prev Next

葛根在治療糖尿病和戒酒中的應(yīng)用

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Applications of Pueraria lobata in treating diabetics and reducing alcohol drinking

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    摘要:
    葛根（Pueraria lobata）是中國傳統(tǒng)上最重要的藥用植物之一。根據(jù)《傷寒論》（外感熱病論）記載，傳統(tǒng)上可用于解熱、眼睛酸痛、口干及與高血壓相關(guān)的頭痛和頸部僵直等癥狀。20世紀70年代的研究表明，從葛根中提取的異黃酮是愈風寧心片主要的生物活性成分，可用于治療中風后的患者。本文回顧了葛根在治療糖尿病和戒酒方面的最新應(yīng)用。由于葛根毒性較低，是用于開發(fā)治療人類疾病的植物藥的良好機遇。

    Abstract:
    Pueraria lobata is one of the most important medicinal herbs used traditionally in China. According to Shanghan Lun (Treatise on Exogenous Febrile Disease), it has been used traditionally to relieve body heat, eye soring, dry mouth, headache associated with high blood pressure, and stiff neck problems. Modern studies in the 1970s revealed that isoflavonoids extracted from P. lobata were the bioactive components of an herbal remedy namely Yufeng Ningxin Tablets for the treatment of patients after stroke. This article reviews recent application of P. lobota in the treatment of diabetics and in reducing alcohol drinking. In view of its low toxicity profile, P. lobota stands an excellent chance to be developed as a phytomedicine for treating human diseases.

    關(guān)鍵詞:
    糖尿病;葛根;野葛;戒酒

    Keywords:


    Project Supported:
    grants from NIH (1R42AA022577)

    Clc Number:

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