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Archive > Volume 13 Issue 1 > 2021,13(1). DOI:10.1016/j.chmed.2020.12.003 Prev Next

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Panax japonicus and chikusetsusaponins: A review of diverse biological acivities and pharmacology mechanism

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    摘要:


    Abstract:
    Panax japonicus, which in the Tujia dialect is known as “Baisan Qi” and “Zhujieshen”, is a classic “qi” drug of Tujia ethnomedicine and it has unique effects on disease caused by “qi” stagnation and blood stasis. This paper serves as the basis of further scientific research and development of Panax japonicus. The pharmacology effects of molecular pharmacology were discussed and summarized. P. japonicus plays an important role on several diseases, such as rheumatic arthritis, cancer, cardiovascular agents, and this review provides new insights into P. japonicus as promising agents to substitute ginseng and notoginseng.

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    Project Supported:
    This work was financially supported by Natural Science Foundation of Hunan Province (No. 2017JJ5041, 2018JJ2293), the National Key R&D Program of China (No. 2018YFC1707900), National Natural Science Foundation of China (No. 81874369, 81803708, 81673579 and 81374062), Key Research and Development Programs of Hunan Science and Technology Department (No. 2018SK2113, 2018SK2119, 2018WK2081).

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