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Archive > Volume 13 Issue 2 > 2021,13(2):250-254. DOI:10.1016/j.chmed.2020.09.003 Prev Next

Original articles

Insights for integrative medicinal potentials of Ethiopian Kale (Brassica carinata): Investigation of antibacterial, antioxidant potential and phytocompounds composition of its leaves

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    摘要:


    Abstract:
    Objective: To compare the phytochemical and antimicrobial activity of Ethiopian Kale leaves infusions, investigate the antioxidant activity and profile the major phytochemicals existing in the better solvent system. Methods: Ethiopian Kale leaves were collected from Addis Ababa, Ethiopia, and extracted using different solvents. The qualitative phytochemical analysis, antibacterial assays, and Fourier Transform Infrared (FTIR) analysis are executed for all extracts. Antioxidant assay and Gas Chromatography-Mass Spectrometry (GC-MS) analysis are carried out for the solvent system, which showed better activity in preliminary studies. Results: The qualitative phytochemical analysis exposed the presence of different classes of phytoconstituents in most of the tested extracts. The broad spectrum of antibacterial activity (7–15 mm) was noted against the tested bacterial species. The functional groups of the extracts are reported by FTIR analysis. The antioxidant ability of ethanol extract was found to be (62.92 ± 0.34)% for 2,2-diphenyl-1-picrylhydrazyl (DPPH*) assay and (71.12 ± 0.41)% for 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assay. More than 17 major phytocompounds in ethanol extract was profiled by GC-MS analysis. Conclusion: The ethanol extract of Ethiopian Kale leaves contain a good source of phytochemicals and it can be a significant source for various functional applications.

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    Project Supported:
    The authors are thankful to Addis Ababa Science and Technology University, Ethiopia for providing partial financial support (Grant Reference No-AASTU-SSRF-CBCE-BT-2018) and lab facilities for this work.

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