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Archive > Volume 17 Issue 1 > 2025,17(1):19-30. DOI:https://doi.org/10.1016/j.chmed.2024.10.001 Prev Next

三葉五加的植物化學(xué)、分析方法和藥理學(xué)研究進(jìn)展：一種有開發(fā)價(jià)值、有前途的藥用和食用資源

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Advances in phytochemistry, ananlysis methods and pharmacology of Eleutherococcus trifoliatus: A promising medicinal and edible resource with development value

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    摘要:
    三葉五加（Eleutherococcus trifoliatus (L.) S. Y. Hu）在中國被稱為白簕或簕菜，是一種在民間傳統(tǒng)中廣泛使用的藥食兩用植物。作為傳統(tǒng)中草藥，三葉五加具有清熱解毒、祛風(fēng)除濕、活血化瘀、鎮(zhèn)痛、止咳平喘的功效。研究發(fā)現(xiàn)其所含化學(xué)成分較多，包括二萜皂苷、三萜皂苷、苯丙素、黃酮、木脂素、咖啡酸單寧、甾類、揮發(fā)油等，其中黃酮、皂苷和咖啡酸單寧是最具活性的成分。體外和體內(nèi)藥理實(shí)驗(yàn)表明，三葉五加具有抗炎、降糖、抗癌、抗氧化、抗菌、抗過敏、抗疲勞、鎮(zhèn)痛和止血作用。本文對(duì)三葉五加在植物化學(xué)、分析方法和藥理學(xué)方面的研究進(jìn)展進(jìn)行綜述。

    Abstract:
    Eleutherococcus trifoliatus (Araliaceae) is called Baile or Lecai in China. E. trifoliatus is a medicinal and edible plant widely used in folk traditions. As a TCM, the dried herb of this species can remove damp heat and detoxicity, cure rheumatism, remove blood stasis, relieve pain, and alleviate cough and asthma symptoms. Many chemical compounds have been reported including diterpenoids, triterpenoids, phenylpropanoids, flavonoids, lignans, caffeoyl quinic acids, steroids, essential oils, etc., in which flavonoids, saponins, and caffeoyl quinic acids are the most bioactive components. In vitro and in vivo pharmacological experiments demonstrated that E. trifoliatus has anti-inflammatory, hypoglycemic, anticancer, antioxidant, antibacterial, anti-hyperalgesic, anti-fatigue, analgesic, and hemostatic effects. Here we reviewed E. trifoliatus in phytochemistry, analysis methods, and pharmacology.

    關(guān)鍵詞:
    五加科;分析方法;抗炎;三葉五加;藥理學(xué);植物化學(xué);毒性

    Keywords:


    Project Supported:
    This work was supported by Natural Science Foundation of Hunan Province (No. 2023JJ60213 and 2024JJ7357); The Key Discipline of Biological Engineering in the Fourteenth Five-year Plan of Hunan University of Chinese Medicine [XiaoXingFaGuiZi-2023-No.2]; Hunan Provincial Innovation Foundation for Postgraduate (No. QL20220186); Scientific Research Program of Hunan Provincial Education Department (No. 23C0155); The Key Discipline of Pharmacy in Hunan Province.

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