[關(guān)鍵詞]
[摘要]
姜黃素是姜黃屬植物中的主要活性成分,具有抗癌、抗氧化、抗炎、清除自由基、抗微生物以及對心血管系統(tǒng)、消化系統(tǒng)等多方面藥理作用,有較好的臨床應(yīng)用價值和研發(fā)潛力。隨著提取分離技術(shù)的發(fā)展,目前有多種方法從植物中提取精制姜黃素。對近年來研究姜黃素的酶法、超臨界CO2萃取法等提取方法,聚酰胺吸附、大孔樹脂吸附等分離方法及其在保護心腦血管和抗腫瘤等方面的藥理作用進行綜述,為進一步開發(fā)利用姜黃素提供依據(jù)。
[Key word]
[Abstract]
Curcumin is one of the major active ingredients in plants of Curcuma L. and has many pharmacological effects, such as anti-cancer, anti-oxidant, anti-inflammatory, free radical scavenging, and anti-microbial effect in the cardiovascular system and digestive system, and so on. It has better clinical application and developping potential of new drug. With the development of extraction and isolation technology, there are many ways to extract refined curcumin from plants. The recent studies of curcumin extraction methods, i.e. enzyme method and supercritical CO2, separation methods, i.e. polyamide adsorption, macroporous resin adsorption, pharmacological effects of proventing cardio-cerebro-vascular and anti-tumor are reviewed to provide the basis evidence for further utilization of curcumin.
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[基金項目]