目的 研究影響清腦降壓滴丸成型的因素，確定最佳制備工藝。方法 通過單因素篩選和正交試驗設計，進行清腦降壓滴丸的制備工藝條件的研究。結果 優(yōu)選的最佳成型工藝為藥物與基質配比為1∶2、基質為聚乙二醇6000、滴制溫度為75 ℃、冷卻液溫度為10 ℃。結論 優(yōu)選的清腦降壓滴丸成型工藝簡便易行，成品得率高，丸質量差異、崩解時限符合要求。

Objective To optimize the technical parameters on Qingnao Jiangya Dropping Pills. Methods To investigate the preparation technique and optimal formulation of Qingnao Jiangya Dropping Pills based on the studies of influential factors, optimal formulation was obtained by the orthogonal design. Results The optimum molding parameters were as follows: the ratio between drug and matrix was 1∶2, matrix was PEG 6000, dropping temperature was 75 ℃, the cooling fluid temperature was 10 ℃. Conclusion The optimization of the molding process is simple, high-yield, and the weight deviation and the disintegration time conform to the standard.