目的 研究無糖型寧心安神糖漿（SNAS）的鎮(zhèn)靜、催眠作用。方法 采用自主活動試驗、戊巴比妥鈉閾上催眠劑量試驗、睡眠試驗、戊巴比妥鈉閾下催眠劑量試驗，每個試驗均選擇ICR小鼠60只，隨機分為6組，每組10只，分別為空白對照組，安神補腦液組，蔗糖型寧心安神糖漿組，SNAS高、中、低劑量（100、50、25 mL/kg）組，觀察SNAS對小鼠的鎮(zhèn)靜和催眠作用。結(jié)果 SNAS能明顯減少小鼠的自主活動次數(shù)，增加閾下劑量戊巴比妥鈉致小鼠入睡數(shù)量，延長小鼠睡眠時間，縮短入睡潛伏期。結(jié)論 無糖型寧心安神糖漿具有明顯的鎮(zhèn)靜、催眠作用。

Objective To study the sedative and hypnotic effects of Sugar-free Ningxin Anshen Syrup (SNAS). Methods The effects of SNAS on sedation and hypnotism in mice were observed by spontaneous behavior test, pentobarbital sodium hypnosis test (subthreshold and suprathreshold dosages), and sleeping test, in which 60 ICR mice were randomly divided into six groups such as control, Anshenbunao Syrup, Ningxin Anshen Syrup, and SNAS high-, mid-, and low-dose (100, 50, and 25 mL/kg) groups. Results SNAS could apparently inhibit the spontaneous behavior, increase the number of sleeping mice by pentobarbital sodium (subthreshold dosage), prolong the sleeping time, and shorten the sleeping latent period of mice. Conclusion SNAS has obvious sedative and hypnotic effects.

科技部“十一五”重大新藥創(chuàng)制項目（2010ZX09401-402）