[關(guān)鍵詞]
[摘要]
目的 通過給予冠心病心絞痛氣虛血瘀證患者芪參益氣滴丸及西藥治療,探討其療效及對(duì)中醫(yī)癥狀的影響。方法 將59例冠心病心絞痛氣虛血瘀證患者隨機(jī)分為西藥組(29例)和西藥+中藥組(30例)。西藥治療:參照美國(guó)心臟病學(xué)院/美國(guó)心臟學(xué)會(huì)/美國(guó)醫(yī)師學(xué)院聯(lián)合議定的冠心病心絞痛診斷及治療指南;中藥治療:給予芪參益氣滴丸0.5 g,tid,治療60 d。觀察治療前后心絞痛療效、硝酸甘油停減率及中醫(yī)癥狀評(píng)分變化。結(jié)果 治療后,西藥+中藥組心絞痛總有效率及硝酸甘油停減率高于西藥組,但2組比較無統(tǒng)計(jì)學(xué)意義(P>0.05);治療后,2組胸痛、胸悶癥狀明顯改善,2組與治療前比較有顯著差異性(P<0.01);西藥組氣短、乏力、心悸、自汗、面色少華癥狀無明顯改善,與治療前比較無差異性(P>0.05)。西藥+中藥組氣短、乏力、心悸、自汗、面色少華癥狀明顯改善,與治療前比較有顯著差異性(P<0.01),西藥+中藥組中醫(yī)癥狀的改善優(yōu)于西藥組,且有顯著差異性(P<0.01)。結(jié)論 聯(lián)合應(yīng)用芪參益氣滴丸及西藥能有效地改善冠心病心絞痛氣虛血瘀證患者的療效及中醫(yī)癥狀,值得臨床推廣。
[Key word]
[Abstract]
Objective To investigate the effect of Qishen Yiqi Dripping Pills (QYDP) with western medicine on the deficiency of vital energy and blood stasis (DVEBS) of patients suffered from coronary heart disease (CHD)-caused angina pectoris. Methods Fifty-nine patients with DVEBS of CHD-caused angina pectoris were randomly divided into two groups, they are western medicine (WM, 29 patients) group and western + traditional Chinese medicines (WTCM, 30 patients) group. The therapy of WM group was in accordance with the guideline for diagnose and therapy of CHD-caused angina pectoris by American College of Cardiology (ACC)/American Heart Association (AHA)/American College of Physicians (ACP). The therapy of TCM was administration with 0.5 g QYDP once for three times daily and the treatment course was 60 d. The changes of curative effect on angina pectoris, stopping and decreasing rate of Nitroglycerin, and the score of TCM were observed. Results After 60 d treatment, the total effective rate and the stopping and decreasing rates of Nitroglycerin in WTCM group were higher than those in WM group, but there was no statistical significance (P>0.05). After the treatment, the symptoms of chest pain and dyspnea were significantly improved in both groups (P<0.01); The symptoms of short breath, acratia, cardiopalmus, spontaneous perspiration, and vultus were not significantly improved in WM group (P>0.05) but significantly improved in WTCM group (P<0.01). The symptoms in WTCM group were more significantly improved than those in WM group (P<0.01). Conclusion The therapeutic effect could be effectively improved by QYDP with western medicine in the patients with DVEBS of CHD-caused angina pectoris.
[中圖分類號(hào)]
[基金項(xiàng)目]