目的 研究新疆阿魏樹脂的化學(xué)成分。方法 利用硅膠、ODS柱色譜、HPLC色譜及反復(fù)重結(jié)晶等方法進(jìn)行分離純化，根據(jù)理化性質(zhì)及波譜分析對(duì)分離得到的化合物進(jìn)行結(jié)構(gòu)鑒定。結(jié)果 分離得到6個(gè)化合物，分別鑒定為7-羥基香豆素（1）、香草醛（2）、松柏醛（3）、3-(3,4-二甲氧基苯基)-2-丙烯醛（4）、阿魏酸（5）和β-谷甾醇（6）。結(jié)論 化合物3、4均為首次從該屬植物中分離得到，化合物2為首次從新疆阿魏中分離得到。

Objective To study the chemical constituents in resin of Ferula sinkiangensis. Methods The compounds were isolated by chromatography on silica gel and ODS column, HPLC, recrystallization and the structures were identified on the basis of physicochemical constants and spectral analyses. Results Six compounds were obtained and their structures were identified as 7-hydroxycoumain (1), vanillin (2), coniferyl aldehyde (3), 3-(3,4-dimethoxyphenyl)-2-propenal (4), ferulic acid (5), and β-sitosterol (6). Conclusion Compounds 3 and 4 are isolated from the plants of Ferula L. for the first time and compound 2 is isolated from F. sinkiangensis for the first time.

國(guó)家自然科學(xué)基金資助項(xiàng)目（81060332）