目的 觀察昆明山海棠口腔膜對(duì)糜爛型口腔扁平苔蘚的臨床療效。方法 166例糜爛型口腔扁平苔蘚患者隨機(jī)分為治療組（84例）和對(duì)照組（82例），治療組給予昆明山海棠口腔膜每日2次，治療4周；對(duì)照組給予醋酸地塞米松粘貼片每日2次，治療4周。治療結(jié)束時(shí)用客觀指標(biāo)和主觀指標(biāo)分別評(píng)價(jià)療效?？陀^指標(biāo)：由觀察者測(cè)算病損面積的大??；主觀指標(biāo)：采用直觀類比標(biāo)尺法（VAS），紀(jì)錄疼痛程度。結(jié)果 兩組患者病損面積和VAS指標(biāo)都有明顯下降，治療組總有效率為86.90%，對(duì)照組總有效率為81.70%，兩組差異無(wú)統(tǒng)計(jì)學(xué)意義（P＞0.05）。結(jié)論 昆明山海棠口腔膜治療糜爛型口腔扁平苔蘚取得較好的療效，具有臨床推廣價(jià)值。

Objective To evaluate the clinical efficacy of Tripterygium hypoglaucum oral membrane on erosive oral lichen planus. Methods A total of 166 patients with erosive oral lichen planus were randomly divided into treatment (84) and control (82) groups. The patients in the treatment group were received T. hypoglaucum oral membrane twice daily for four weeks; The patients in the control group were received Dexamethasone Acetateadhesive Tablets twice daily for four weeks. The clinical efficacies were measured by objective and subjective indicators at the end of treatment. Objective indicators included the size of the lesion area were estimated by the observer; Subjective indicators included a visual analog scale (VAS) was used to record the degree of pain. Results Patients in the two groups showed the significant reduction in erosive areas and VAS scores. The total effective rates in the treatment group and control group were 86.90% and 81.70%, respectively, and there was no statistical significance (P>0.05). Conclusion T. hypoglaucum oral membrane has better clinical efficacy on erosive oral lichen planus, which is worth of spreading in clinic.

天津醫(yī)科大學(xué)第二醫(yī)院科研基金項(xiàng)目（y0503）