目的 探討萬古霉素致不良反應的特點及相關因素，為臨床合理用藥提供參考。方法 檢索2001—2013年國內醫(yī)藥期刊報道的40例萬古霉素致不良反應案例，并進行統(tǒng)計、分析。結果 萬古霉素所致不良反應主要表現(xiàn)為藥熱、腎衰竭、過敏反應等。結論 臨床應加強萬古霉素的合理使用，盡量避免或減少其所致不良反應的發(fā)生。

Objective To study the characteristics and related factors of the adverse drug reaction (ADR) induced by vancomycin, so as to provide the references for the rational use of drugs in clinic. Methods Forty cases of ADR induced by vancomycin, which were reported in domestic medical academic journals from 2001 to 2012, were statistically analyzed. Results The ADR induced by vancomycin is mainly radiation, kidney failure, allergic reaction, and so on. Conclusion The rational use of vancomycin should be emphasized to avoid or reduce the incidence of ADR.