目的 研究苦瓜莖葉的化學(xué)成分，為進(jìn)一步開(kāi)發(fā)利用苦瓜莖葉提供依據(jù)。方法 采用反復(fù)硅膠柱色譜、反相ODS柱色譜、Sephadex LH-20等柱色譜進(jìn)行分離純化，通過(guò)波譜數(shù)據(jù)鑒定化合物結(jié)構(gòu)。結(jié)果 分離得到1種倍半萜和2種葫蘆烷三萜，分別鑒定為催吐蘿芙葉醇（1）、kuguacin J（2）、3,23(R)-二羥基-7-乙氧基-19-醛基-5,24-二烯醇（3）。結(jié)論 化合物1為首次從該植物中分離得到，化合物3為新化合物，命名為7-乙基苦瓜素Ⅰ。

Objective To study the chemical constituents from the fresh vines and leaves of Momordica charantia, and to provide a basis for the further development and utilization of bitter melon whole plant. Methods The chemical constituents were isolated and purified by chromatography on silica gel, ODS silica gel, and Sephadex LH-20 columns, and their structures were determined by spectral data. Results One sesquiterpene and two cucurbitane triterpenoids were obtained and they were identified as vomifoliol (1), kuguacin J (2), and 3,23(R)-dihydroxycucurbita-7-ethoxy-5,24-dien-19-al (3). Conclusion Compound 1 is isolated from M. charantia for the first time and compound 3 is a new compound named 7-ethyl momordicine I.