鉤藤是我國(guó)一種常用藥材，對(duì)心血管系統(tǒng)、中樞神經(jīng)系統(tǒng)和血液系統(tǒng)等均具有比較廣泛的藥理活性，臨床上主要用于治療高血壓、焦慮等疾病。現(xiàn)代中藥藥理研究表明，鉤藤對(duì)中樞神經(jīng)系統(tǒng)的藥理作用主要表現(xiàn)為鎮(zhèn)靜、抗癲癇、抗驚厥和對(duì)神經(jīng)元的保護(hù)等，其中對(duì)神經(jīng)元的保護(hù)作用與多種神經(jīng)遞質(zhì)相關(guān)，具有多種作用機(jī)制，已被國(guó)內(nèi)外越來(lái)越多的醫(yī)藥工作者所重視，綜述鉤藤生物堿對(duì)中樞神經(jīng)系統(tǒng)的藥理作用研究進(jìn)展。

Uncariae Ramulus Cum Uncis is a commonly used medicinal herbs in China, which has a relatively wide range of pharmacological activity on the cardiovascular system, central nervous system, and the blood system. It is mainly used to treat hypertension, anxiety and other diseases clinically. Modern Pharmacology studies have shown that the mainly pharmacological effects of Uncaria is sedation, antiepileptic, anticonvulsant, and neuronal protection role on the central nervous system. The protective effect of neurons associated with neurotransmitters that has multifunctional action mechanism, more and more domestic and foreign medical workers have been paid attention to it, this study progress of neural pharmacological effect of rhynchophylline are described below.

安徽省自然科學(xué)基金重點(diǎn)項(xiàng)目（KJ2011A265）