白芍是毛茛科植物芍藥的干燥根，含有多種具有生理活性的化學成分。白芍總苷（TGP）是從白芍中提取的一組糖苷類物質(zhì)的總稱，此糖苷類物質(zhì)包括芍藥苷、芍藥花苷、羥基芍藥苷、苯甲酰芍藥苷、芍藥內(nèi)酯苷等，其中芍藥苷和芍藥內(nèi)酯苷是其主要成分。藥理及臨床研究發(fā)現(xiàn)TGP具有抗炎、調(diào)節(jié)免疫、鎮(zhèn)痛等功效，近年來TGP已被廣泛應用于多種腎臟疾病的臨床治療。就TGP治療腎臟疾病的藥理作用及臨床應用研究進展做一綜述。

Paeoniae Radix Alba is the dried roots of Paeonia lactiflora in Ranunculaceae, which contains a variety of chemical composition with physiological effects. Total glucoside from Paeoniae Radix Alba (TGP) is a general term for a group of glycosides substances which is extracted from Paeoniae Radix Alba. The TGP includes paeoniflorin, peony flower glucoside, hydroxy paeoniflorin, benzoyl paeoniflorin, peony lactone glycosides, and so on. The main compositions are paeoniflorin and peony lactone glycosides. Pharmacological and clinical researches find that TGP has anti-inflammatory, immunomodulatory, and analgesic functions. It has been widely applied in a variety of clinical treatment of kidney disease in recent years. This article makes a summary on the the research progress in pharmacological effects and clinical application of TGP in the treatment of kidney diseases.