目的 探討阿拉瑞林預(yù)防卵巢子宮內(nèi)膜異位囊腫術(shù)后復(fù)發(fā)的臨床療效。方法 回顧性收集2008年3月-2010年12月天津市美中宜和婦兒醫(yī)院收治的卵巢子宮內(nèi)膜異位囊腫（OEC）患者54例為研究對(duì)象，行腹腔鏡下囊腫剔除術(shù)，并于術(shù)后第1次月經(jīng)的第一天給予注射用阿拉瑞林150 μg/d，肌肉注射，連續(xù)5 d，每4周為1個(gè)周期，連續(xù)6個(gè)周期。以同期單純腹腔鏡下囊腫剔除術(shù)的OEC患者50例為對(duì)照。通過(guò)查閱病史，比較兩組患者的臨床療效、復(fù)發(fā)時(shí)間、累積復(fù)發(fā)率和累積生存率。結(jié)果 治療組和對(duì)照組的總有效率分別為92.59%、78.00%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療組平均復(fù)發(fā)時(shí)間（24.69±3.69）個(gè)月，對(duì)照組為（18.65±1.25）個(gè)月，兩組復(fù)發(fā)時(shí)間比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.01）；治療組患者累積復(fù)發(fā)率均明顯低于對(duì)照組，累積生存率明顯高于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.01）。結(jié)論 阿拉瑞林能夠提高OEC患者腹腔鏡下囊腫剔除術(shù)的臨床療效，延長(zhǎng)復(fù)發(fā)時(shí)間，減少?gòu)?fù)發(fā)率，具有重要的預(yù)防價(jià)值。

Objective To investigate the clinical efficacy of alareilin in preventing the recurrence of ovarian endometriosis cyst (OEC) after the operation. Methods Retrospectively collected 54 patients with OEC in Tianjin Meizhong Yihe Women and Children's Hospital from March 2008 to December 2010 as the research object. The patients were accepted the operation of laparoscopic cyst removed, and they were im administered with alareilin 150 μg/d on day 1 of the first menstruation after the operation, and lasted for 5 d. Every 4 week was as one cycle, and they were continuously treated for six cycles. Fifty patients with OEC, who were accepted pure operation of laparoscopic cyst removed in the same period, were as control. Clinical efficacy, recurrence time, accumulated recurrence rate, and cumulative survival rate were compared by referring to the history. Results The total effective rates of the patients in the treatment and control groups were 92.59% and 78.00%, respectively, with the significant difference between the two groups (P < 0.05). The average recurrence time of the patients in the treatment group was (24.69 ± 3.69) months, and that of the patients in the control group was (18.65 ± 1.25) months, with the significant difference between the two groups (P < 0.01). Cumulative recurrence rate of the patients in treatment group was significantly lower than that of the patients in the control group. At the same time, the cumulative survival rate was significantly higher than that in the control group, with the significant difference between the two groups (P < 0.01). Conclusion Alareilin could improve the clinical curative effect of patients with OEC undergoing laparoscopic cyst, and prolong the time of recurrence, reduce the recurrence rate, which has the important value of prevention on recurrence of OEC.