目的 調(diào)查分析天津市腫瘤醫(yī)院抗菌藥物的使用情況.方法 采用橫斷面調(diào)查方法,對天津市腫瘤醫(yī)2014年3月24日00:00～24:00所有住院的腫瘤患者抗菌藥物使用情況進(jìn)行調(diào)查.結(jié)果 1 259例腫瘤住院患者中,抗菌藥物使用率為13.19%,單一用藥率為83.13%,二聯(lián)用藥率為13.86%,三聯(lián)及以上用藥率為3.01%.全院治療性應(yīng)用抗菌藥比例為78.92%,預(yù)防性應(yīng)用比例13.86%,送檢率77.86%.用藥頻率(DDDs)居前三位的依次是碳青霉烯類、第3代頭孢菌素和β內(nèi)酰胺/β內(nèi)酰胺酶抑制劑.結(jié)論 天津市腫瘤醫(yī)院住院患者抗菌藥物應(yīng)用基本合理,但個(gè)別科室仍存在諸多不合理用藥現(xiàn)象,需進(jìn)一步加強(qiáng)管理.

Objective To carry out the cross-sectional survey on utilization of antibiotics in Tianjin Medical University Cancer Institute and Hospital. Methods In cross-sectional survey, the clinical utilization of all inpatients from 0 to 24 h on March 24th 2014 was surveyed. Results Among 1 259 inpatients, the cross-sectional use rate of antibiotics was 13.19%, of which rate of single-drug was 83.13%, rate of double-drug was 13.86%, and rate of triple-drug and above was 3.01%. The therapeutic use rate of antibiotics was 78.92%, and the prophylactic use rate was 13.86%. Rate of etiological examination for therapeutic medication was 77.86%. The top three antibiotics in the list of DDDs were carbapenems, third generation of cephalosporins, and β-lactam/β-lactamase inhibitors. Conclusions In Tianjin Medical University Cancer Institute and Hospital, the cross-sectional application rate of antibiotics is reasonable, but there is also some phenomenon of many unreasonable medicines in some department, which needs further efforts to strengthen the management.