目的 了解精神疾病合并高血壓患者的抗高血壓藥物應用情況.方法 采用橫斷面調(diào)查方法,對廣州市精神病醫(yī)院2014年4月22日00:00～24:00時精神疾病合并高血壓住院患者的抗高血壓藥物的臨床應用進行調(diào)查.結果 212例住院患者中,精神分裂癥合并高血壓患者占50%,發(fā)病率男性高于女性,50歲以上發(fā)病率較高.抗高血壓藥物使用頻率排名前5位的依次是左氨氯地平片(23.24%)、厄貝沙坦片(14.07%)、硝苯地平控釋片(12.23%)、氨氯地平片(10.70%)、美托洛爾片(10.09%).治療方案中,單一用藥124例(58.49%),二聯(lián)用藥75例(35.38%),三聯(lián)用藥13例(6.13%).結論 該院抗高血壓藥的使用能夠做到個體化用藥,治療高血壓的方案基本合理.

Objective To understand the utilization of antihypertensive drugs in patients with mental disease complicated with hypertension. Methods In cross-sectional survey, the clinical utilization of all inpatients with mental disease complicated with hypertension from 00:00 to 24:00 h on April 22th 2014 was surveyed. Results Among 212 inpatients, patients with schizophrenia complicated with hypertension accounted to 50%. It affected more men than women. And the age of patients with high prevalence were more than 50 years old. The top 5 antihypertensive drugs were Levamlodipine Besylate Tablets (23.24%), Irbesartan Tablets (14.07%), Nifedipine Controlled Release Tablets (12.23%), Amlodipine Tablets (10.70%), and Metoprolol Tablets (10.09%). In therapeutic schedule, the usage of single-drug was 124 cases (58.49%), usage of double-drug was 75 cases (35.38%), and usage of triple-drug was 13 cases (6.13%). Conclusion The application of antihypertensive drugs is individual and the therapeutic schedule is reasonable.