目的 研究2011—2013年常熟市第一人民醫(yī)院抗菌藥物的使用情況和發(fā)展趨勢(shì),為規(guī)范合理用藥提供參考.方法 選取2011—2013年使用抗菌藥物治療的患者648例進(jìn)行回顧性分析,分別從抗菌藥物科室分布、使用品種、聯(lián)合用藥、銷售金額、使用頻度(DDDs)、限定日費(fèi)用(DDDc)等方面進(jìn)行統(tǒng)計(jì)分析,對(duì)抗菌藥物使用的基本情況進(jìn)行匯總分析.結(jié)果 在調(diào)查的648例病例中,ICU患者抗菌藥物使用所占比例最高,同時(shí)治療類藥物的使用大于預(yù)防類藥物.抗菌藥物聯(lián)用情況明顯,占到總數(shù)的20%左右,單獨(dú)使用一種抗菌藥物時(shí),藥物多為一線藥物,價(jià)格較高.2011—2013年頭孢類藥物的銷售金額、DDDs、DDDc均排在最前面,表明頭孢類藥物使用率高.結(jié)論 2011—2013年常熟市第一人民醫(yī)院抗菌藥物的使用基本合理,但有部分科室、部分藥物使用情況不合理,還需進(jìn)一步加強(qiáng)管理.

Objective To study the utilization and trends of antimicrobial drugs in Changshu No. 1 People's Hospital from 2011 to 2013, and to provide a reference for standardizing the rational use of drugs. Methods The utilization of antimicrobial drugs to patients (648 cases) was summarized retrospectively, and department distribution, varieties, drug combination, consumption sum, frequency of drug use (DDDs), and defined daily cost (DDDc) were analyzed statistically. Results In 648 patients, there were the most patients using antimicrobial drugs in ICU. And antimicrobial drugs for treatment were used more than those for prevention. Drug combination was quite common, accounting for about 20%. Most of the single medication were first-line and expensive drugs. Consumption sum, DDDs, and DDDc of cephalosporins ranked the first during 2011—2013, indicating that the utilization rate of cephalosporins was high. Conclusion The utilization of antimicrobial drugs is basically rational in Changshu No. 1 People's Hospital during 2011—2013, but there is also some unreasonable medication in some departments and some antimicrobial drugs, which needs further efforts to strengthen the management.