目的 分析2011—2014年天津醫(yī)科大學第二醫(yī)院抗菌藥物的使用情況,為合理使用抗菌藥物提供依據(jù).方法 采用回顧性調查方法對天津醫(yī)科大學第二醫(yī)院2011—2014年抗菌藥物的使用情況進行匯總,對抗菌藥物的品種、銷售金額、用藥頻度(DDDs)以及日均費用(DDC)進行分析.結果 2011—2014年抗菌藥物銷售金額比例逐年下降,抗菌藥物品種數(shù)也呈下降趨勢;注射劑型和口服劑型中頭孢菌素類藥物連續(xù)4年銷售量和DDDs均是第一位,注射劑型的增幅大于口服劑型;注射用頭孢地嗪鈉的DDDs排名連續(xù)4年均為第一位,且2014年增長幅度最大.同種藥品不同年份的DDC值略有差異.結論 2011—2014年天津醫(yī)科大學第二醫(yī)院抗菌藥物的使用總體規(guī)范合理,抗菌藥物應用總量及品種數(shù)均降低且更加合理,與此同時也發(fā)現(xiàn)一些問題,還需進一步加強管理.

Objective To analyze the utilization of antibacterial drugs in the Second Hospital of Tianjin Medical University from 2011 to 2014, and to provide valuable reference for rational use of antibacterial drugs. Methods The utilization of antibacterial drugs in the Second Hospital of Tianjin Medical University from 2011 to 2014 was summarized retrospectively, and the varieties, costs, defined daily doses (DDDs), and defined daily cost (DDC) were analyzed. Results From 2011 to 2014, the proportion of the consumption sum of antibacterial drugs was declining year by year, and several varieties of antibiotics decreased, too. Sales and DDDs of cephalosporins in injection or oral dosage forms both ranked the first for the last four years. The increase of injections was bigger than that of oral dosage forms. DDDs of Cefodizime Sodium for injection ranked the first for the last four years, and the increase in 2014 was the biggest. DDC of the same drug in different years had little difference. Conclusion In general, the utilization of antibacterial drugs in the Second Hospital of Tianjin Medical University from 2011 to 2014 is up to reasonable standard, and the total number of antibacterial drugs and varieties are lower and more reasonable. At the same time, there are also some problems, which need further efforts to strengthen the management.