目的 對(duì)淄博市中心醫(yī)院中藥注射劑超說明書用藥情況進(jìn)行調(diào)查分析, 為臨床合理用藥提供參考。方法 隨機(jī)抽取2014年淄博市中心醫(yī)院使用中藥注射劑的住院患者病歷200份, 對(duì)中藥注射劑的溶媒選擇、用藥劑量或濃度、用藥療程、超適應(yīng)癥用藥等進(jìn)行分析評(píng)價(jià)。結(jié)果 中藥注射劑臨床使用廣泛。中藥注射劑存在一定程度溶媒選擇不當(dāng)、超劑量、超濃度或超療程用藥等超說明書用藥的情況, 超說明書用藥處方占42%。結(jié)論 加強(qiáng)處方點(diǎn)評(píng)與反饋, 對(duì)超說明書用藥進(jìn)行有效干預(yù), 促進(jìn)中藥注射劑的合理使用。

Objective To investigate the off-label use of traditional Chinese medicine (TCM) injection in Central Hospital of Zibo, and to provide reference for reasonable application of TCM injection. Methods In-patients (200 cases) using TCM injection in Central Hospital of Zibo in 2014 were randomly extracted, and the selection of solvent, drug dosage or concentration, course of medication, and ultra-indication of TCM injection were analyzed and evaluated. Results TCM injection were widely used in Central Hospital of Zibo. There was a certain degree of off-label use of drugs, including unreasonable choice of solvent, ultra-dosage, ultra-concentration, and ultra-course of medication. The prescription of off-label use of TCM injection accounted for 42%. Conclusion Prescription comments and feedback should be strengthened, and off-label use of TCM injection should be given effective intervention, to promote rational use of TCM injection.

山東省藥學(xué)會(huì)臨床藥學(xué)奧賽康中青年科研資助項(xiàng)目(Sdpa-ask-2013-01)