肉蓯蓉為臨床常用中藥, 有“沙漠人參”之稱(chēng)。肉蓯蓉的化學(xué)成分主要包括苯乙醇苷類(lèi)、生物堿類(lèi)、環(huán)烯醚萜苷類(lèi)、有機(jī)酸類(lèi)、木脂素苷以及一些揮發(fā)性成分。其藥理作用主要表現(xiàn)為促激素樣作用、促進(jìn)免疫、抗氧化、抗衰老、通便等作用。主要對(duì)肉蓯蓉炮制的歷史沿革及現(xiàn)代炮制工藝、炮制前后化學(xué)成分和藥理作用的變化進(jìn)行綜述, 以期為深入開(kāi)展炮制研究及原理解析提供文獻(xiàn)依據(jù)。

Cistanches Herba is the clinical common Chinese drug, and known as "desert ginseng" in the desert. The main chemical constituents isolated from Cistanches Herba are phenylethanoid glycosides, alkaloids, iridoid glycosides, organic acids, lignans glycosides, and some volatile components, etc. The major pharmacological effects of Cistanches Herba are hormone-like stimulation, immune promotion, anti-oxidation, anti-aging, and laxative action. The processing history, modern processing technology, the changes of chemical constituents and pharmacological effects before and after processing are reviewed in this paper, which could provide a documentation basis for further research on processing technology and explanation of processing mechanism.

國(guó)家自然科學(xué)基金資助項(xiàng)目(81473350);國(guó)家自然科學(xué)基金青年基金資助項(xiàng)目(81001635)