目的 了解天津市腫瘤醫(yī)院麻醉藥品的使用情況和變化趨勢,為促進(jìn)臨床合理用藥提供依據(jù)。方法 對2011—2014年天津市腫瘤醫(yī)院麻醉藥品的用量、銷售金額、用藥頻度(DDDs)、日均藥費(fèi)(DDC)及藥品排序比(B/A)等進(jìn)行統(tǒng)計(jì)和分析。結(jié)果 2011—2014年麻醉藥品的銷售金額及構(gòu)成比均逐年增加;芬太尼透皮貼劑的銷售金額在各年度均占絕對優(yōu)勢并逐年上升。麻醉藥品的DDDs排名比較穩(wěn)定,芬太尼透皮貼劑的DDDs排名持續(xù)第1位。除鹽酸嗎啡注射液、硫酸嗎啡片、磷酸可待因片、鹽酸布桂嗪注射液、鹽酸布桂嗪片與鹽酸哌替啶注射液在2014年的DDC出現(xiàn)增長,其余麻醉藥品的DDC基本穩(wěn)定。硫酸嗎啡緩釋片、枸櫞酸芬太尼注射液、磷酸可待因片的B/A都大于1,注射用鹽酸瑞芬太尼與枸櫞酸舒芬太尼注射液均小于1,其余藥物的B/A均接近1。結(jié)論 天津市腫瘤醫(yī)院麻醉藥品的應(yīng)用基本合理,但仍存在一些不足,還需進(jìn)一步加強(qiáng)管理。

Objective To investigate the usage and variation tendency of narcotic drugs in Tianjin Cancer Hospital, in order to provide reference for rational drug use in clinic. Methods The utilization, consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) of narcotic drugs in Tianjin Cancer Hospital during 2011—2014 were calculated and analyzed. Results During 2011—2014, the consumption sum and constituent ratios of narcotic drugs increased year by year. The consumption sum of Fentanyl Transdermal Patches ranked the first, and increased year by year. The rank of DDDs was stable, and DDDs of Fentanyl Transdermal Patches ranked the first persistently. DDC of Morphine Hydrochloride Injection, Morphine Sulfate Tablets, Codeine Phosphate Tablets, Bucinnazine Hydrochloride Injection, Ucinnazine Hydrochloride Tablets, and Pethidine Hydrochloride Injection in 2014 increased, while DDC of others were stable. B/A of Morphine Sulfate Sustained Release Tablets, Fentanyl Citrate Injection, and Codeine Phosphate Tablets were above 1, while B/A of Remifentanil Hydrochloride for injection and Sufentanil Citrate Injection were lower than 1. The others were close to 1. Conclusion The utilization of narcotic drugs in Tianjin Cancer Hospital is rational on the whole, but there are still some problems, which needs further efforts to strengthen the management.