目的 了解吉林大學(xué)中日聯(lián)誼醫(yī)院麻醉藥品的應(yīng)用情況及用藥趨勢(shì),為臨床合理用藥提供參考。方法 對(duì)吉林大學(xué)中日聯(lián)誼醫(yī)院2012—2014年麻醉藥品的用藥金額、使用量、用藥頻度(DDDs)、日均藥費(fèi)(DDC)等情況進(jìn)行統(tǒng)計(jì)分析。結(jié)果 麻醉藥品的銷(xiāo)售金額和構(gòu)成比逐年增加;口服劑型的使用量逐年增長(zhǎng),且增長(zhǎng)速度快;外用劑型的使用量變化不大,有小幅下降趨勢(shì)。芬太尼注射液、舒芬太尼注射液、鹽酸嗎啡緩釋片及鹽酸羥考酮緩釋片(10 mg)的DDDs位列前4位,鹽酸羥考酮注射液、舒芬太尼注射液、注射用鹽酸瑞芬太尼、芬太尼透皮帖劑的DDC位列前4位。結(jié)論 吉林大學(xué)中日聯(lián)誼醫(yī)院麻醉藥品的應(yīng)用基本合理,但仍有不足之處,有待進(jìn)一步加強(qiáng)干預(yù)和管理。

Objective To investigate the usage and trend of narcotic drugs in China-Japan Union Hospital of Jilin University, so as to provide reference for clinical rational use of narcotic drugs. Methods The usage amount, consumption sum, defined daily doses (DDDs), and daily drug cost (DDC) of narcotic drugs in China-Japan Union Hospital of Jilin University from 2012 to 2014 were analyzed statistically. Results The consumption sum and constituent ratio of narcotic drugs increased year by year. The usage amount of oral narcotics increased year by year with high speed. The usage amount of external formulation had a little change, and had a trend of slight decline. DDDs of Fentanyl Injection, Sufentanil Citrate Injection, Morphine Hydrochloride Sustained-release Tablets, and Oxycodone Hydrochloride Prolonged-release Tablets (10 mg) took up the top 4. Oxycodone Hydrochloride Injection, Sufentanil Citrate Injection, Remifentanil Hydrochloride for Injection, and Fentanyl Transdermal Patch ranked the top 4 in the list of DDC. Conclusion The use of narcotic drugs in China-Japan Union Hospital of Jilin University is basically reasonable, but there are also some deficiencies, which need further efforts to strengthen the intervention and management.