目的 了解遼寧省腫瘤醫(yī)院麻醉藥品的應(yīng)用現(xiàn)狀及變化趨勢,為臨床合理用藥提供參考。方法 收集遼寧省腫瘤醫(yī)院2013—2014年麻醉藥品的應(yīng)用數(shù)據(jù),對其用量、銷售金額、用藥頻度(DDDs)、日均藥費(fèi)(DDC)及藥品排序比(B/A)等進(jìn)行統(tǒng)計(jì)和分析。結(jié)果 2013—2014年用量排前兩位的為磷酸可待因片和鹽酸羥考酮緩釋片(10 mg);芬太尼透皮貼劑(8.4 mg)與鹽酸羥考酮緩釋片(40 mg)位列銷售金額的前兩位。芬太尼透皮貼劑(40 mg)與枸櫞酸芬太尼注射液的DDDs始終保持在前兩位,但有下降的趨勢。枸櫞酸舒芬太尼注射液、注射用鹽酸瑞芬太尼、鹽酸羥考酮緩釋片(10 mg)的DDC居前3位。B/A接近1的藥品包括芬太尼透皮貼劑、鹽酸嗎啡注射液、鹽酸嗎啡片、鹽酸哌替啶注射液、阿片片。結(jié)論 遼寧省腫瘤醫(yī)院麻醉藥品的應(yīng)用基本合理。

Objective To investigate the usage and variation tendency of narcotic drugs in Liaoning Cancer Hospital and Institute, and to provide reference for rational drug use in clinic. Methods The data of narcotic drugs in Liaoning Cancer Hospital and Institute from 2013 to 2014 were collected, and the consumption quantity, consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were calculated and analyzed. Results During 2013—2014, the top two consumption quantity of narcotic drugs were Codeine Phosphate Tablets and Oxycodone Hydrochloride Prolonged-release Tablets (10 mg). Consumption sum of Fentanyl Transdermal Patches (8.4 mg) and Oxycodone Hydrochloride Prolonged-release Tablets (40 mg) ranked the top two. DDDs of Fentanyl Transdermal Patches (40 mg) and Fentanyl Citrate Injection ranked the first two persistently, but they had a tendency to decline. DDC of Sufentanil Citrate Injection, Remifentanil Hydrochloride for injection, and Oxycodone Hydrochloride Prolonged-release Tablets (10 mg) ranked the top three. The narcotic drugs whose B/A was close to 1 included Sufentanil Citrate Injection, Morphine Hydrochloride Injection, Morphine Hydrochloride Tablets, Pethidine Hydrochloride Injection, and Opium Tablets. Conclusion The utilization of narcotic drugs in Liaoning Cancer Hospital and Institute is basically reasonable.