目的 觀察復(fù)方白及乳膏聯(lián)合邁之靈片治療肛裂的臨床療效。方法 選取2014年6月-2015年6月十堰市太和醫(yī)院肛腸科收治的早期肛裂患者76例。按入選順序排序編號,奇數(shù)為治療組,偶數(shù)為對照組,每組各38例。對照組涂抹龍珠軟膏,2次/d;治療組涂抹復(fù)方白及乳膏,2次/d。兩組患者同時(shí)口服邁之靈片,2片/次,2次/d。7 d為1個(gè)療程,連續(xù)治療2個(gè)療程。觀察兩組的臨床療效,同時(shí)比較兩組治療前后便血消失時(shí)間、疼痛消失時(shí)間、創(chuàng)面愈合時(shí)間。結(jié)果 治療后,對照組和治療組的治愈率分別為78.9%、92.1%,總有效率均為100.0%,兩組治愈率比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05),但總有效率比較差異無統(tǒng)計(jì)學(xué)意義。治療后,治療組患者便血消失時(shí)間、疼痛消失時(shí)間、創(chuàng)面愈合時(shí)間均顯著短于對照組,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 復(fù)方白及乳膏聯(lián)合邁之靈片治療肛裂具有較好的臨床療效,能顯著改善臨床癥狀,具有良好的臨床應(yīng)用價(jià)值。

Objective To observe the clinical effects of Compound Baiji Cream combined with Aescuven Forte Tablets in treatment of anal fissure. Methods Patients (76 cases) with early anal fissure in Department of Anus-intestines of Shiyan Taihe Hospital from June 2014 to June 2015 were divided into control and treatment groups according to the visiting single or even numbers, and each group had 38cases. The patients in the control group were administered with Longzhu Ointment, twice daily. The patients in the treatment group were administered with Compound Baiji Cream, twice daily. The patients in two groups were po administered with Aescuven Forte Tablets 2 tablets/time, twice daily. Seven days was a course, and the patients in two groups were treated for 2 courses. After treatment, the clinical efficacies were evaluated, and the periods of healing pain, hemafecia, and wound healing in two groups before and after treatment were compared. Results After treatment, the cure rates in the control and treatment groups were 78.9% and 92.1%, respectively, and there were differences between two groups (P < 0.05). And the clinical efficacies in two groups were both 100.0%, but there were no differences between two groups. After treatment, the periods of healing pain, hemafecia, and wound healing in the treatment group were significantly shorter than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Compound Baiji Cream combined with Aescuven Forte Tablets has clinical curative effect in treatment of anal fissure, can improve the clinical efficacies, which has a certain clinical application value.

湖北省科學(xué)技術(shù)鑒定成果項(xiàng)目(EK2014D150024000699);太和科研資助項(xiàng)目(2013JJXM021)