目的 研究醒腦靜注射液聯(lián)合注射用尤瑞克林治療老年腦梗死的臨床療效。方法 選取2012年4月-2015年4月銅川市人民醫(yī)院神經(jīng)內(nèi)科收治的老年腦梗死患者100例，隨機(jī)分為對照組和治療組，每組各50例。對照組患者在常規(guī)治療的同時靜脈滴注注射用尤瑞克林，0.15 PNA單位，用100 mL生理鹽水溶解，1次/d。治療組在對照組治療的基礎(chǔ)上靜脈滴注醒腦靜注射液，10 mL/次加入5%葡萄糖注射液250 mL中，1次/d。兩組均連續(xù)治療15 d。觀察兩組的臨床療效，同時比較治療前后兩組神經(jīng)功能缺損（NIHSS）評分、大腦中動脈（MCA）的峰流速（Vp）、平均流速（Vm）的變化情況。結(jié)果 治療后，對照組和治療組的總有效率分別為68.0%、84.0%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者NIHSS評分顯著降低，Vp、Vm顯著升高，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療組這些指標(biāo)的改善程度優(yōu)于對照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 醒腦靜注射液聯(lián)合注射用尤瑞克林治療老年腦梗死具有較好的臨床療效，可降低NIHSS評分，改善患者腦血流動力學(xué)，具有一定的臨床推廣應(yīng)用價值。

Objective To investigate the efficacy of Xingnaojing Injection combined with urinary kallidinogenase in treatment of senium cerebral infarction. Methods Patients (100 cases) with senium cerebral infarction in Tongchuan People's Hospital from April 2013 to April 2015 were randomly divided into control and treatment groups, and each group had 50 cases. The patients in the control group were iv administered with Urinary Kallidinogenase for injection on the basis of conventional treatment, 0.15 PNA U added into normal saline 100 mL, once daily. The patients in the treatment group were iv administered with Xingnaojing Injection on the basis of the control group, 10 mL/time added into 5% glucose injection 250 mL, once daily. The patients in two groups were treated for 15 d. After treatment, the clinical efficacies were evaluated, and the change of the NIHSS scores, Vp and Vm of MCA in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 68.0% and 84.0%, respectively, and there were differences between two groups (P<0.05). After treatment, NIHSS scores in two groups were significantly decreased, and Vp and Vm of MCA were significantly increased, and the difference was statistically significant in the same group (P<0.05). After treatment, those observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Xingnaojing Injection combined with urinary kallidinogenase in treatment of senium cerebral infarction, and can reduce the NIHSS score, also can improve the cerebral blood flow dynamics, which has a certain clinical application value.