目的 觀(guān)察楓蓼腸胃康片聯(lián)合奧美拉唑和復(fù)方嗜酸乳桿菌治療急性胃腸炎的臨床療效。方法 選取2015年2月-2016年2月在建始縣中醫(yī)院接受治療的急性胃腸炎患者94例，隨機(jī)分為對(duì)照組和治療組，每組各47例。兩組患者均給予急性胃腸炎的對(duì)癥治療。對(duì)照組口服奧美拉唑腸溶片，20 mg/次，1次/d；同時(shí)口服復(fù)方嗜酸乳桿菌片，1 g/次，3次/d。治療組在對(duì)照組的基礎(chǔ)上口服楓蓼腸胃康片，4片/次，3次/d。兩組患者均連續(xù)治療2周。觀(guān)察兩組的臨床療效，同時(shí)比較治療前后兩組的臨床癥狀評(píng)分，以及血清降鈣素（PCT）、白細(xì)胞介素-6（IL-6）和IL-8的水平變化。結(jié)果 治療后，對(duì)照組的總有效率為82.98%，治療組為95.74%，兩組總有效率比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。兩組的臨床癥狀評(píng)分和總積分均較治療前顯著降低（P<0.05），且與對(duì)照組相比，治療組降低更為明顯，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。兩組PCT、IL-6、IL-8水平均較治療前明顯下降（P<0.05），且治療組的血清學(xué)指標(biāo)水平較對(duì)照組下降的更為明顯（P<0.05）。結(jié)論 楓蓼腸胃康片聯(lián)合奧美拉唑和復(fù)方嗜酸乳桿菌治療急性胃腸炎療效顯著，可明顯改善患者臨床癥狀，減輕機(jī)體炎癥反應(yīng)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical curative effect of Fengliao Changweikang Tablets combined with omeprazole and compound eosinophil-lactobacillus in treatment of acute gastroenteritis. Methods Patients (94 cases) with acute gastroenteritis in Jianshi Hospital of TCM from February 2015 to February 2016 were randomly divided into control and treatment groups. Each group had 47 cases. All patients were given symptomatic treatment of acute gastroenteritis. Patients in the control group were po administrated with Omeprazole Enteric-coated Tablets, 20 mg/time, once daily. And they were po administered with Compound Eosinophil-Lactobacillus Tablets, 1 g/d, three times daily. On the basis of control group, patients in the treatment group were po administrated with Fengliao Changweikang Tablets, 4 tablets/time, three times daily. Two groups were treated for 2 weeks. After treatment, the efficacy was evaluated, clinical symptom scores and levels of serum PCT, IL-6, and IL-8 between two groups were compared. Results After treatment, clinical efficacy in the treatment groups was 95.74% which was significantly higher than that (82.98%) of the control group, and the difference was statistically significant between two groups (P<0.05). After treatment, clinical symptom scores and total integral in two groups were obviously decreased (P<0.05). These observational indexes in the treatment group were better than those in the control group, with significant difference between two groups (P<0.05). After treatment, levels of PCT, IL-6 and IL-8 in two groups were significantly decreased (P<0.05), and the decreasing degree of these serological indexes in the treatment group were more obviously than that in the control group (P<0.05). Conclusion Fengliao Changweikang Tablets combined with omeprazole and compound eosinophil-lactobacillus has a good clinical curative effect in treatment of acute gastroenteritis in treatment of acute gastroenteritis, can significantly improve the clinical symptoms, and relieve inflammatory reaction, which has a certain clinical application value.