目的 分析天津市武清區(qū)中醫(yī)醫(yī)院女性泌尿生殖道感染的病原菌分布和耐藥性情況，為臨床合理用藥提供依據(jù)。方法 選擇2013年1月-2015年1月在天津市武清區(qū)中醫(yī)醫(yī)院就診的泌尿生殖道感染女性患者120例，對(duì)病原菌分布和藥敏結(jié)果進(jìn)行回顧性分析。結(jié)果 共分離出病原菌380株，其中支原體274株，占72.11%，主要為解脲支原體和人型支原體；細(xì)菌106例，占27.89%，主要為腸桿菌、表皮葡萄球菌和金黃色葡萄球菌。解脲支原體對(duì)環(huán)丙沙星、紅霉素、氧氟沙星、四環(huán)素的耐藥率較高，均大于60.00%；人型支原體對(duì)環(huán)丙沙星、紅霉素、氧氟沙星、四環(huán)素、阿奇霉素、氯霉素、克拉霉素、復(fù)方新諾明耐藥率較高，均大于60.00%，解脲支原體和人型支原體對(duì)多西環(huán)素、米諾環(huán)素、交沙霉素的耐藥率較低，均小于10.00%；表皮葡萄球菌和金黃色葡萄球菌對(duì)環(huán)丙沙星、紅霉素、氯霉素的耐藥率較高，均大于70.00%，腸桿菌對(duì)環(huán)丙沙星、氧氟沙星、紅霉素的耐藥率均大于70.00%，表皮葡萄球菌、腸桿菌、金黃色葡萄球菌對(duì)交沙霉素、多西環(huán)素、米諾環(huán)素的耐藥率均小于10.00%。結(jié)論 天津市武清區(qū)中醫(yī)醫(yī)院女性生殖道感染病原菌以支原體為主，其中多數(shù)耐藥嚴(yán)重，臨床應(yīng)結(jié)合藥敏試驗(yàn)，合理選用抗菌藥物；同時(shí)要重視加強(qiáng)細(xì)菌耐藥性的檢測(cè)。

Objective To analyze the distribution and drug resistance of pathogenic bacteria causing female urogenital tract infection in Tianjin Wuqing Hospital of TCM, and to provide reference for clinical rational drug use. Methods Female patients (120 cases) with urogenital tract infection were selected in Tianjin Wuqing Hospital of TCM from January 2013 to January 2015. The distribution and drug resistance were analyzed retrospectively. Results Total 380 strains of pathogens were isolated, in which mycoplasma were 274 strains (72.11%), main of them were Mycoplasma urealyticum and M. humenis. While bacteria (106 strains) accounted for 27.89%, main of them were Enterobacter bacilli, Staphylococcus epidermidis, and S. aureus. The resistance rates of M. urealyticum against ciprofloxacin, erythromycin, ofloxacin, and tetracycline were higher, and they were all above 60.00%. The resistance rates of M. humenis against ciprofloxacin, erythromycin, ofloxacin, tetracycline, azithromycin, chloramphenicol, and trimethoprim/sulfamethoxazole were higher, and they were all above 60.00%. M. urealyticum and M. humenis were more sensitive to doxycycline, minocycline, and josamycin, and the resistance rates were all lower than 10.00%. The resistance rates of S. epidermidis, and S. aureus against ciprofloxacin, erythromycin, and chloramphenicol were higher, and they were all above 70.00%. The resistance rates of E. bacilli against ciprofloxacin, ofloxacin, and erythromycin were higher, and they were all above 70.00%. S. epidermidis, E. bacilli, and S. aureus were more sensitive to josamycin, doxycycline, and minocycline, and the resistance rates were all lower than 10.00%. Conclusion The main pathogenic bacteria causing female urogenital tract infection in Tianjin Wuqing Hospital of TCM is mycoplasma, and most of them were severely resistant to antibiotics. It is important to choose rational antibiotics according to the drug sensitive test and enhance the detection of drug resistance.