[關(guān)鍵詞]
[摘要]
目的 探討婦康片聯(lián)合醋酸甲羥孕酮治療單純型子宮內(nèi)膜增生癥的臨床療效。方法 選取2015年3月-2016年3月在陜西中醫(yī)藥大學(xué)第二附屬醫(yī)院接受治療的單純型子宮內(nèi)膜增生癥患者78例,隨機(jī)分組法分為對(duì)照組和治療組,每組各39例。對(duì)照組口服醋酸甲羥孕酮片,2 mg/次,3次/d。治療組在對(duì)照組基礎(chǔ)上口服婦康片,5片/次,2次/d。兩組患者均治療14 d。觀察兩組的臨床療效,比較兩組子宮內(nèi)膜厚度、月經(jīng)失血評(píng)估表(PBAC)評(píng)分、血紅蛋白(Hb)和醫(yī)院焦慮抑郁量表(HAD)評(píng)分情況。結(jié)果 治療后,對(duì)照組和治療組的總有效率分別為79.49%、94.87%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組子宮內(nèi)膜厚度、PBAC評(píng)分和HAD評(píng)分均顯著降低,而Hb顯著生高,同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療組這些觀察指標(biāo)的改善程度明顯優(yōu)于對(duì)照組,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 婦康片聯(lián)合醋酸甲羥孕酮治療單純型子宮內(nèi)膜增生癥具有較好的臨床療效,可改善臨床癥狀,緩解焦慮和抑郁情緒,具有一定的臨床推廣應(yīng)用價(jià)值。
[Key word]
[Abstract]
Objective To investigate the clinical effect of Fukang Tablets combined with medroxyprogesterone acetate in treatment of simple endometrial hyperplasia. Methods Patients (78 cases) with simple endometrial hyperplasia in the Second Affiliated Hospital of Shaanxi University of Chinese Medicine from March 2015 to March 2016 were randomly divided into the control and treatment groups, and each group had 39 cases. Patients in the control group were po administered with Medroxyprogesterone Acetate Tablets, 2 mg/time, three times daily. Patients in the treatment group were po administered with Fukang Tablets on the basis of the control group, 5 tablets/time, twice daily. After treatment, the clinical efficacies were evaluated, and endometrial thickness, PBAC scores, Hb, and HAD scores in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 79.49% and 94.87%, respectively, and there was difference between two groups (P<0.05). After treatment, endometrial thickness, PBAC scores, and HAD scores in two groups were significantly decreased, but Hb in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Fukang Tablets combined with medroxyprogesterone acetate has clinical curative effect in treatment of simple endometrial hyperplasia, and can improve clinical symptoms, relieve anxiety and depression, which has a certain clinical application value.
[中圖分類號(hào)]
[基金項(xiàng)目]