目的 了解武漢大學(xué)人民醫(yī)院抗精神病藥物的使用情況，為醫(yī)護人員提供參考。方法 選取武漢大學(xué)人民醫(yī)院2014年9月-2016年9月154份腦器質(zhì)性精神病患者病歷進行回顧性分析，對患者的性別、年齡、病因、用藥方案、抗精神病藥物的使用情況以及不良反應(yīng)進行分類統(tǒng)計。結(jié)果 154例腦器質(zhì)性精神病患者中，男性多于女性；年齡多是大于40歲的中老年患者；病因復(fù)雜，多集中在腦血管疾病、腦萎縮、腦白質(zhì)病3大原因；精神病表現(xiàn)綜合征主要為精神病性癥狀，腦器質(zhì)性精神病治療方案多采用精神藥物聯(lián)用的方案，且奧氮平是臨床上最常用的腦器質(zhì)性精神病的治療藥物。結(jié)論 從藥物流行病學(xué)角度考察了武漢大學(xué)人民醫(yī)院腦器質(zhì)性精神病的藥物利用模式，對臨床制訂抗精神病藥物治療方案有積極意義。

Objective To realize the utilization of antipsychotic drugs in Renmin Hospital of Wuhan University, in order to provide a reference for medical staff. Methods Records of 154 patients with brain organic mental disorder in Renmin Hospital of Wuhan University from September 2014 to September 2016 were analyzed. Gender, age, etiology, drug programs, utilization of antipsychotic drugs, and drug adverse reactions were classified statistically. Results In patients (154 cases) with brain organic mental disorders, men were more than women, and patients above 40 years old were more focused. Etiology was complex, and more were focused on cerebrovascular diseases, cerebral atrophy, and leukoencephalopathy. Psychotic symptoms were the main form of organic mental disorder. Most patients with brain organic mental disorder used more than one antipsychotic drug. Additionally, olanzapine was the most common administrated drug in the hospital. Conclusion The drug utilization pattern of antipsychotics in Renmin Hospital of Wuhan University is discussed in the view of drug epidemiology, and it may have positive meaning for clinic to make antipsychotic medication for organic mental disorders.