目的 探討松齡血脈康膠囊聯(lián)合坎地沙坦酯片治療更年期女性陰虛陽(yáng)亢型高血壓的療效觀察。方法 選取2015年3月-2015年10月在天津市中醫(yī)藥研究院附屬醫(yī)院就診的陰虛陽(yáng)亢型更年期女性原發(fā)性高血壓患者70例，隨機(jī)分為對(duì)照組和治療組，每組各35例。對(duì)照組口服坎地沙坦酯片，8 mg/次，1次/d。治療組在對(duì)照組基礎(chǔ)上口服松齡血脈康膠囊，1.5 g/次，3次/d。兩組患者均持續(xù)治療8周。觀察兩組的臨床療效，比較兩組的血壓和中醫(yī)證候積分情況。結(jié)果 治療后，對(duì)照組和治療組的血壓療效總有效率分別為74.28%、85.71%，中醫(yī)證候療效總有效率分別為68.57%、88.57%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組收縮壓和舒張壓均明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的下降程度明顯優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組眩暈、頭痛、五心煩熱、心悸失眠的中醫(yī)證候積分均明顯下降，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且治療組這些觀察指標(biāo)的下降程度明顯優(yōu)于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 松齡血脈康膠囊聯(lián)合坎地沙坦酯片治療更年期女性陰虛陽(yáng)亢型高血壓具有較好的臨床療效，能顯著降低血壓，改善臨床癥狀，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To observe the clinical effect of Songling Xuemaikang Capsules combined with Candesartan Cilexetil Tablets in treatment of climacteric hypertension with Yin deficiency and Yang hyperactivity. Methods Climacteric women (70 cases) with hypertension hyperactivity in Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital from March 2015 to October 2015 were randomly divided into control and treatment groups, and each group had 35 cases. Patients in the control group were po administered with Candesartan Cilexetil Tablets, 8 mg/time, once daily. Patients in the treatment group were po administered with Songling Xuemaikang Capsules on the basis of the control group, 1.5 g/time, three times daily. Patients in two groups were treated for 8 weeks. After treatment, the clinical efficacies were evaluated, and blood pressure and Traditional Chinese Medicine syndrome scores in two groups were compared. Results After treatment, the clinical efficacies of blood pressure in the control and treatment groups were 74.28% and 85.71%, respectively, and the clinical efficacies of Traditional Chinese Medicine syndrome in the control and treatment groups were 68.57% and 88.57%, respectively, and there were difference between two groups (P<0.05). After treatment, systolic pressure and diastolic pressure in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the Traditional Chinese Medicine syndrome scores of dizziness, headache, feverish sensation over the five centers (palms, soles, and chest), palpitation, and insomnia in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Songling Xuemaikang Capsules combined with Candesartan Cilexetil Tablets has clinical curative effect in treatment of climacteric hypertension with Yin deficiency and Yang hyperactivity, can significantly decrease blood pressure, and improve clinical symptoms, which has a certain clinical application value.