目的 分析2014-2016年北京大學深圳醫(yī)院曲美他嗪處方的使用情況，為促進臨床合理用藥提供依據(jù)。方法 抽取2014-2016年北京大學深圳醫(yī)院使用曲美他嗪的處方，并進行回顧性分析。結(jié)果 2015年處方量變化不大，但2016年處方量明顯下降。2014-2016年開具曲美他嗪處方的科室類別和排名變化不大，主要是心血管內(nèi)科、特診老年病科。2016年超適應(yīng)癥用藥處方量明顯減少，但禁忌癥使用人次明顯高于2014、2015年。結(jié)論 曲美他嗪在臨床上仍然存在不合理用藥情況，需要更多的研究以助于科學地評估和分析效益-風險比。

Objective To analyze the utilization of trimetazidine prescription in Peking University Shenzhen Hospital from 2014 to 2016. Methods Trimetazidine prescription in Peking University Shenzhen Hospital from 2014 to 2016 was extracted and analyzed retrospectively. Results The quantity of trimetazidine prescription in 2015 was near to that in 2014, but the amount of prescriptions was obviously decreased in 2016. The category and rank of department had little change from 2014 to 2016, and the trimetazidine prescription was chiefly prescribed by the departments of cardiovascular medicine and special clinic geriatrics. The prescription amount of off-label use was obviously decreased in 2016, while the number of contraindication was obviously higher than that in 2014 and 2015. Conclusions There is still some irrational drug use in clinic, therefore more researches are needed for evaluation on benefit-risk balance.