目的 探討血塞通注射液聯(lián)合鹽酸倍他司汀治療后循環(huán)缺血性眩暈的臨床療效。方法 選取2015年10月-2016年10月在南陽市第九人民醫(yī)院進(jìn)行治療的后循環(huán)缺血性眩暈患者94例，根據(jù)治療方案的不同分為對照組（47例）和治療組（47例）。對照組靜脈滴注鹽酸倍他司汀注射液，20 mg加入5%葡萄糖溶液250 mL中，1次/d。治療組在對照組的基礎(chǔ)上靜脈滴注血塞通注射液，10 mL加入5%葡萄糖溶液250 mL中，1次/d。兩組患者均連續(xù)治療2周。觀察兩組患者臨床療效，同時(shí)比較治療前后兩組患者椎基底動(dòng)脈平均血流速度、血液流變學(xué)指標(biāo)和眩暈癥狀評分變化。結(jié)果 治療后，對照組和治療組的總有效率分別為80.85%、95.74%，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者左、右椎動(dòng)脈及基底動(dòng)脈平均血流速度均較治療前明顯升高（P<0.05）；且治療后治療組椎基底動(dòng)脈平均血流速度改善更顯著（P<0.05）。治療后，兩組患者全血黏度（WBV）、血漿黏度（PV）、纖維蛋白原（FIB）和血小板黏附率（PAR）等指標(biāo)均較治療前顯著降低（P<0.05）；且治療后治療組患者的血液流變學(xué)指標(biāo)水平顯著優(yōu)于對照組（P<0.05）。治療后，兩組患者眩暈癥狀評分均明顯降低（P<0.05）；且治療后治療組患者眩暈癥狀評分降低程度顯著優(yōu)于對照組（P<0.05）。結(jié)論 血塞通注射液聯(lián)合鹽酸倍他司汀治療后循環(huán)缺血性眩暈的臨床效果顯著，可明顯改善患者眩暈癥狀，增加椎基底動(dòng)脈血供，降低血液黏度。

Objective To investigate the clinical effect of Xuesaitong Injection combined with betahistine in treatment of posterior circulation ischemia vertigo. Methods Patients (94 cases) with posterior circulation ischemia vertigo in the Ninth People's Hospital of Nanyang from October 2015 to October 2016 were divided into control (47 cases) and treatment (47 cases) groups based on different treatments. Patients in the control group were iv administered with Betahistine Hydrochloride Injection, 20 mg added into 5% glucose solution (250 mL), once daily. Patients in the treatment group were iv administered with Xuesaitong Injection on the basis of the control group, 10 mL added into 5% glucose solution (250 mL), once daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacies in two groups were evaluated, the changes of average blood flow velocity of vertebrobasilar artery, hemorheology index, and vertigo symptom score in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 80.85% and 95.74% respectively, and there was difference between two groups (P < 0.05). After treatment, the mean blood flow velocity of left and right vertebral artery and basilar artery in two groups was significantly increased (P < 0.05). And the average blood flow velocity of vertebrobasilar artery in the treatment group was increased more significantly than that in the control group (P < 0.05). After treatment, the WBV, PV, FIB, and PAR in two groups were significantly decreased (P < 0.05). And the hemorheology index in the treatment group was significantly better than that in the control group (P < 0.05). After treatment, the vertigo symptom scores in two groups were significantly decreased (P < 0.05). And the decrease degree of vertigo symptom score in treatment group was significantly better than that in the treatment group (P < 0.05). Conclusion Xuesaitong Injection combined with betahistine has significant clinical effect in treatment of posterior circulation ischemia vertigo, can obviously improve the vertigo symptoms and increase basilar artery blood supply with reducing blood viscosity.