目的 探討心脈隆注射液聯(lián)合多巴胺治療慢性心力衰竭的臨床療效。方法 選取2015年1月-2016年2月濮陽(yáng)市油田總醫(yī)院收治的慢性心力衰竭患者66例，隨機(jī)分為對(duì)照組和治療組，每組各33例。對(duì)照組靜脈滴注鹽酸多巴胺注射液，30 mg/次，1次/d。治療組在對(duì)照組的治療基礎(chǔ)上靜脈滴注心脈隆注射液，5~10 mg/kg加入生理鹽水250 mL，2次/d。兩組均連續(xù)治療14 d。觀察兩組的臨床療效，比較兩組治療前后爬樓梯階數(shù)、左心室舒張末期內(nèi)徑（LVEDD）、左心室收縮末期內(nèi)徑（LVESD）和左室射血分?jǐn)?shù)（LVEF）的變化情況。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為75.76%、93.94%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者爬樓梯階數(shù)、LVEF顯著升高，LVEDD、LVESD顯著降低，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，治療組爬樓梯階數(shù)、LVEF高于對(duì)照組，LVEDD、LVESD低于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 心脈隆注射液聯(lián)合多巴胺治療慢性心力衰竭具有較好的臨床療效，可顯著改善患者的運(yùn)動(dòng)耐力和心功能相關(guān)指標(biāo)，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To investigate the curative effect of Xinmailong Injection combined with dopamine in treatment of chronic heart failure. Methods Patients (66 cases) with chronic heart failure in Puyang Oilfield General Hospital from January 2015 to February 2016 were randomly divided into control and treatment groups, and each group had 33 cases. Patients in the control group were iv administered with Dopamine Hydrochloride Injection, 30 mg/time, once daily. Patients in the treatment group were iv administered with Xinmailong Injection, 5 - 10 mg/kg added into 250 mL normal saline, twice daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy was evaluated, and the changes of climb the stairs orders, LVEDD, LVESD, and LVEF in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 75.76% and 93.94%, respectively, and there was difference between two groups (P < 0.05). After treatment, the number of climbing stairs and LVEF in two groups were significantly increased, but LVEDD and LVESD were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). After treatment, the number of climbing stairs and LVEF in the treatment group were more than those in the control group, while LVEDD and LVESD in the treatment group were less than those in the control group, and there were differences between two groups (P < 0.05). Conclusion Xinmailong Injection combined with dopamine has significant clinical efficacy in treatment of chronic heart failure, and can significantly improve the exercise endurance and heart function correlation indexes, which has a certain clinical application value.