目的 探討馬來酸麥角新堿注射液聯(lián)合垂體后葉注射液治療產(chǎn)后出血的臨床療效。方法 選取2015年1月-2017年1月在鄭州大學(xué)第五附屬醫(yī)院接受治療的產(chǎn)后出血患者86例，所有入選患者采用隨機數(shù)字表法隨機分為對照組和治療組，每組各43例。對照組于分娩后靜脈滴注垂體后葉注射液，6 U加入到5%葡萄糖注射液500 mL中，滴速0.02~0.04 U/min。治療組在對照組基礎(chǔ)上肌肉注射馬來酸麥角新堿注射液0.2 mg，必要時可2~4 h重復(fù)注射1次，最多5次。觀察兩組的臨床療效，比較兩組的產(chǎn)后出血量和止血時間。結(jié)果 治療后，對照組和治療組的總有效率分別為81.40%、95.35%，兩組比較差異有統(tǒng)計學(xué)意義（P<0.05）。用藥后30 min、2 h、24 h后，治療組產(chǎn)后出血量均明顯少于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）；治療后，治療組止血時間明顯短于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 馬來酸麥角新堿注射液聯(lián)合垂體后葉注射液治療產(chǎn)后出血具有較好的臨床療效，可減少出血量，縮短止血時間，具有一定的臨床推廣應(yīng)用價值。

Objective To investigate the clinical effect of Ergometrine Maleate Injection combined with Posterior Pituitary Injection in treatment of postpartum hemorrhage. Methods Patients (86 cases) with postpartum hemorrhage in the Fifth Affiliated Hospital of Zhengzhou University from January 2015 to January 2017 were randomly divided into control and treatment groups, and each group had 43 cases. Patients in the control group were iv administered with Posterior Pituitary Injection after childbirth, 6 U added into 5% glucose solution 500 mL, drop speed 0.02 - 0.04 U/min. Patients in the treatment group were iv administered with Ergometrine Maleate Injection for 0.2 mg on the basis of the control group, if necessary, 2 - 4 h repeated one time, up to 5 times. After treatment, the clinical efficacies were evaluated, and the amount of postpartum hemorrhage and hemostasis time in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 81.40% and 95.35%, respectively, and there was difference between two groups (P < 0.05). After treatment for 30 min, 2 h, and 24 h, the amount of postpartum hemorrhage in the treatment group was significantly lower than that in the control group, and there was difference between two groups (P < 0.05). After treatment, hemostasis time in the treatment group was significantly shorter than that in the control group, and there was difference between two groups (P < 0.05). Conclusion Ergometrine Maleate Injection combined with Posterior Pituitary Injection has clinical curative effect in treatment of postpartum hemorrhage, and can reduce the amount of bleeding, and shorten hemostasis time, which has a certain clinical application value.