目的 分析葛根素注射液所致不良反應(yīng)（ADR）的特點(diǎn)，為臨床合理用藥提供參考。方法 檢索中國(guó)學(xué)術(shù)期刊（網(wǎng)絡(luò)版）、中國(guó)生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫(kù)（CBM）、萬方數(shù)字化期刊全文庫(kù)、中文科技期刊全文數(shù)據(jù)庫(kù)（維普）等數(shù)據(jù)庫(kù)報(bào)道的葛根素注射液致ADR的文獻(xiàn)，并進(jìn)行分析和討論。結(jié)果 葛根素注射液所致ADR男性明顯多于女性，年齡多集中在50歲以上；心血管系統(tǒng)疾病患者的ADR最多，構(gòu)成比為53.6%；絕大多數(shù)患者的給藥劑量為400、500 mg/d，構(gòu)成比分別為47.55%、26.57%；絕大多數(shù)患者（117例，62.23%）給藥療程為14 d；用藥0.5～24 h的患者最多，占21.88%；ADR累及器官/系統(tǒng)以變態(tài)反應(yīng)較為多見，構(gòu)成比分別為14.36%。結(jié)論 加強(qiáng)葛根素注射液ADR監(jiān)測(cè)，確?；颊吲R床用藥安全有效。

Objective To analyze the characteristics of adverse drug reactions (ADR) induced by Puerarin Injection, and to provide references for rational use in clinic. Methods China Journal Full-text Database (CNKI), Chinese biomedical literature database (CBM), Wanfang Database, Chinese Science and Technology Journal Full-text Database (VIP), etc were retrieved, and the documents of adverse drug reaction induced by Puerarin Injection were analyzed and discussed. Results Men with ADR induced by Puerarin Injection were more than women, and more were focused on above 50 years old. Patients with cardiovascular system diseases had the most ADR cases, and the constituent ratio was 53.6%. The administration dosages of most patients were 400 and 500 mg/d, respectively, accounting for 47.55% and 26.57%. Patients with course of treatment of 14 d had the highest ADR incidence. The most cases (21.88%) occured in the medication 0.5-24 h. Organs/systems involved by ADR mainly were allergic reaction, accounting for 14.36%. Conclusion ADR of Puerarin Injection should be closely monitored in order to ensure the safety and efficiency of drug use in patients.