目的 觀察婦科再造膠囊聯(lián)合炔諾酮治療無排卵型功能性子宮出血的臨床療效。方法 選取2015年7月—2016年6月在監(jiān)利縣人民醫(yī)院就診的無排卵型功能性子宮出血患者106例，隨機分為對照組和治療組，每組各53例。對照組口服復方炔諾酮片，5 mg/次，1次/8 h，血止后逐漸調(diào)整為2.5 mg/次維持，自血止日算起，連服22 d。1個月經(jīng)周期為1個療程，停藥后待月經(jīng)來潮第5天開始進行下一周期治療。治療組在對照組的基礎上于經(jīng)前1周開始口服婦科再造膠囊，10粒/次，2次/d。1個月經(jīng)周期為1個療程。兩組患者均治療3個療程。評價治療后兩組患者臨床療效，同時比較治療前后兩組臨床改善情況以及雌激素（E₂）、孕酮（P）和血紅蛋白（Hb）水平變化。結(jié)果 治療后，對照組和治療組總有效率分別為75.47%和90.57%，兩組比較差異具有統(tǒng)計學意義（P< 0.05）。治療后，兩組患者月經(jīng)周期和經(jīng)期時間均顯著趨于正常范圍，子宮內(nèi)膜厚度也明顯改善，同組治療前后比較差異具有統(tǒng)計學意義（P< 0.05）；且治療組臨床改善情況明顯好于對照組，兩組比較差異具有統(tǒng)計學意義（P< 0.05）。治療后，兩組患者E₂和P均顯著降低，Hb水平明顯升高，同組比較差異具有統(tǒng)計學意義（P< 0.05）；且治療組E₂、P和Hb水平顯著優(yōu)于對照組，兩組比較差異具有統(tǒng)計學意義（P< 0.05）。結(jié)論 婦科再造膠囊聯(lián)合炔諾酮治療功能性子宮出血臨床療效確切，癥狀體征明顯改善，具有一定的臨床推廣應用價值。

Objective To observe the clinical efficacy of Fuke Zaizao Capsules combined with norethindrone in treatment of anovulatory dysfunctional uterine bleeding. Methods Patients (106 cases) with anovulatory dysfunctional uterine bleeding in Jianli People's Hospital from July 2015 to June 2016 were randomly divided into control and treatment groups, and each group had 53 cases. Patients in the control group were po administered with Compound Norethisterone Tablets, 5 mg/time, once every 8 h, and the dosage was adjusted to 2.5 mg/time gradually after blood stopped, they were treated for 22 d from the day of the bleeding stopped. One menstrual cycle was as one course of treatment. After stopping the drugs, the next treatment cycle begined after the fifth day of menstruation. Patients in the treatment group were po administered with Fuke Zaizao Capsules 1 week before menstruation on the basis of the control group, 10 grains/time, twice daily. One menstrual cycle was as one course of treatment. Patients in two groups were treated for 3 courses. After treatment, clinical efficacy was evaluated, and the clinical improvement, the changes of E₂, P, and Hb levels in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 75.47% and 90.57%, respectively, and there were differences between two groups (P < 0.05). After treatment, the menstrual cycle and menstrual period in two groups significantly tended to normal range, endometrial thickness were also significantly improved, and the difference was statistically significant in the same group (P < 0.05). And the clinical improvement in the treatment group was significantly better than that in the control group, with significant difference between two groups (P < 0.05). After treatment, the E₂ and P levels in two groups were significantly decreased, Hb level was significantly increased, and there were differences in the same group (P < 0.05). And the E₂, P, and Hb levels in treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). Conclusion Fuke Zaizao Capsules combined with norethindrone has definite clinical efficacy in treatment of anovulatory dysfunctional uterine bleeding with obvious improvement of symptoms and signs, which has a certain clinical application value.