[關(guān)鍵詞]
[摘要]
目的 探討健脾生血顆粒聯(lián)合多糖鐵復(fù)合物治療妊娠合并缺鐵性貧血的臨床療效。方法 選取2016年1月-2016年10月在海南醫(yī)學(xué)院第一附屬醫(yī)院接受診治的妊娠合并缺鐵性貧血患者96例,根據(jù)治療方案差異分為對(duì)照組(48例)和治療組(48例)。對(duì)照組患者口服多糖鐵復(fù)合物膠囊,2粒/次,1次/d。治療組在對(duì)照組的基礎(chǔ)上口服健脾生血顆粒,3袋/次,3次/d。兩組患者均連續(xù)治療4周。比較治療前后兩組患者臨床療效,以及血紅蛋白(Hb)、紅細(xì)胞計(jì)數(shù)(RBC)、血清鐵蛋白(SF)和總鐵結(jié)合力(TIBC)水平變化。結(jié)果 治療后,對(duì)照組臨床總有效率為81.25%,顯著低于治療組的97.92%,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組患者Hb、RBC、SF較同組治療前均明顯升高,TIBC明顯降低,同組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療組上述觀察指標(biāo)改善更明顯,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 健脾生血顆粒聯(lián)合多糖鐵復(fù)合物治療妊娠合并缺鐵性貧血效果顯著,安全性高,具有一定的臨床推廣應(yīng)用價(jià)值。
[Key word]
[Abstract]
Objective To investigate the clinical effect of Jianpi Shengxue Granules combined with polysaccharide iron complex in treatment of iron deficiency anemia in pregnancy. Methods Patients (96 cases) with iron deficiency anemia in pregnancy in the First Affiliated Hospital of Hainan Medical University from January 2016 to October 2016 were divided into control (48 cases) and treatment (48 cases) groups based on different treatments. Patients in the control group were po administered with Iron Polysaccharide Complex Capsules, 2 grains/time, once daily. Patients in the treatment group were po administered with Jianpi Shengxue Granules on the basis of the control group, 3 bags/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, clinical efficacy, and the Hb, RBC, SF, and TIBC levels in two groups before and after treatment was compared. Results After treatment, the clinical efficacy in the control group was 81.25%, which was significantly lower than 97.92% in the treatment group, and there were differences between two groups (P<0.05). After treatment, the Hb, RBC, and SF levels in two groups were significantly increased, but TIBC level in two groups was significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the above observation indexes in the treatment group improved more obvious than those in the control group, with significant difference between two groups (P<0.05). Conclusion Jianpi Shengxue Granules combined with polysaccharide iron complex has remarkable effect in treatment of iron deficiency anemia in pregnancy, which has a certain clinical application value.
[中圖分類號(hào)]
[基金項(xiàng)目]