[關(guān)鍵詞]
[摘要]
目的 觀察胃寧散聯(lián)合奧美拉唑治療慢性淺表性胃炎的臨床療效。方法 選取天津市薊州區(qū)出頭嶺醫(yī)院在2014年1月-2016年12月接診的慢性淺表性胃炎患者128例,隨機(jī)分為對照組和治療組,每組各64例。對照組患者飯后口服奧美拉唑腸溶膠囊,40 mg/次,3次/d;治療組在對照組的基礎(chǔ)上口服胃寧散,1袋/次,3次/d。兩組患者治療時間均為6周。比較治療前后兩組患者臨床療效和癥狀評分變化。結(jié)果 治療后,對照組和治療組的總有效率分別為85.94%、93.75%,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。治療后,兩組患者出血、反酸、燒心、上腹脹痛等癥狀評分均顯著下降,同組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);且治療組這些評分低于對照組,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 胃寧散聯(lián)合奧美拉唑治療慢性淺表性胃炎臨床療效顯著,能有效改善患者臨床癥狀,具有一定的臨床推廣應(yīng)用價(jià)值。
[Key word]
[Abstract]
Objective To observe the clinical curative effect of Weining Powder combined with omeprazole in treatment of chronic superficial gastritis. Methods Patients (128 cases) with chronic superficial gastritis in Chutouling Hospital of Tianjin Jizhou District from January 2014 to December 2016 were randomly divided into control and treatment groups, and each group had 64 cases. Patients in the control group were po administered with Omeprazole Enteric-coated Capsules, 40 mg/time, three times daily. Patients in the treatment group were po administered with Weining Powder on the basis of the control group, 1 bag/time, three times daily. Patients in two groups were treated for 6 weeks. After treatment, the change of clinical efficacy and symptom score in two groups before and after treatment was compared. Results After treatment, the clinical efficacy in the control and treatment groups were 85.94% and 93.75%, respectively, and there were differences between two groups (P<0.05). After treatment, the symptom scores of bleeding, acid regurgitation, heartburn and epigastric pain in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). The symptom scores in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Weining Powder combined with omeprazole has obvious curative effect in treatment of chronic superficial gastritis, and can significantly improve clinical symptoms, which has a certain clinical application value.
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