目的 探索復(fù)方甘草酸苷注射液聯(lián)合復(fù)方谷氨酰胺腸溶膠囊治療潰瘍性結(jié)腸炎的臨床療效。方法 選取2014年2月-2017年4月西安市中醫(yī)醫(yī)院收治的124例潰瘍性結(jié)腸炎患者，隨機分為對照組和治療組，每組各62例。對照組口服復(fù)方谷氨酰胺腸溶膠囊，4粒/次，3次/d。治療組患者在對照組治療基礎(chǔ)上靜脈滴注復(fù)方甘草酸苷注射液，20 mL/次加入到生理鹽水500 mL中，1次/d。兩組患者均連續(xù)治療30 d。觀察兩組的臨床療效，比較兩組腹痛程度、疾病活動指數(shù)（DAI）、黏液膿血便消失時間。結(jié)果 治療后，對照組和治療組的總有效率分別為82.26%、96.77%，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組患者腹痛程度評分、DAI指數(shù)均較治療前顯著降低，同組治療前后比較差異具有統(tǒng)計學(xué)意義（P<0.05）；治療后，治療組腹痛程度評分、DAI指數(shù)均低于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）；治療組黏液膿血便消失時間顯著短于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 復(fù)方甘草酸苷注射液聯(lián)合復(fù)方谷氨酰胺腸溶膠囊治療潰瘍性結(jié)腸炎具有較好的臨床療效，可顯著降低腹痛程度，降低DAI指數(shù)，具有一定的臨床推廣應(yīng)用價值。

Objective To explore the clinical efficacy of Compound Glycyrrhizin Injection combined with Compound Glutamine Entersoluble Capsules in treatment of ulcerative colitis. Methods Patients (124 cases) with ulcerative colitis in Xi'an Traditional Chinese Medicine Hospital from February 2014 to April 2017 were randomly divided into control and treatment groups, and each group had 62 cases. Patients in the control group were po administered with Compound Glutamine Entersoluble Capsules, 4 grains/time, three times daily. Patients in the treatment group were iv administered with Compound Glycyrrhizin Injection on the basis of the control group, 20 mL/time added into 500 mL normal saline, once daily. Patients in two groups were treated for 30 d. After treatment, the clinical efficacy was evaluated, and abdominal pain, disease activity index (DAI) and mucus abscess disappeared time in two group were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 82.26% and 96.77%, respectively, with difference between two groups (P<0.05). After treatment, abdominal pain score and disease DAI in two groups significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, abdominal pain score and disease DAI in the treatment group were significantly lower than those in the control group, with difference between two groups (P<0.05). Mucus abscess disappeared time in the treatment group was significantly shorter than that in the control group, and there was difference between two groups (P<0.05). Conclusion Compound Glycyrrhizin Injection combined with Compound Glutamine Entersoluble Capsules has a significant effect in treatment of ulcerative colitis, and can significantly reduce the degree of abdominal pain and reduce the DAI index, which has a certain clinical application value.