目的 了解鄂爾多斯市中心醫(yī)院2014-2016年抗菌藥物的應(yīng)用情況及變化趨勢(shì)，促進(jìn)抗菌藥物使用合理化和規(guī)范化。方法 對(duì)鄂爾多斯市中心醫(yī)院抗菌藥物銷售金額、用藥頻度（DDDs）、日均用藥費(fèi)用（DDC）及各項(xiàng)管理指標(biāo)等進(jìn)行統(tǒng)計(jì)，分析抗菌藥物的應(yīng)用現(xiàn)狀。結(jié)果 2014-2016年，抗菌藥物的銷售金額逐年增加；抗菌藥物的用藥結(jié)構(gòu)比較穩(wěn)定，主要使用的抗菌藥物類別為頭孢菌素類和氟喹諾酮類，碳青霉烯類與抗真菌藥物的DDDs逐年上升，以碳青霉烯類增速最快；DDDs排名前10位的抗菌藥物中絕大多數(shù)藥物的DDC超過100元；抗菌藥物使用強(qiáng)度3年來呈明顯的下降趨勢(shì)，從2014年的48.45 DDD降至2016年的40.20 DDD。結(jié)論 鄂爾多斯市中心醫(yī)院抗菌藥物臨床應(yīng)用存在一定的問題，提示還需加強(qiáng)對(duì)該類藥物的評(píng)價(jià)工作。

Objective To investigate the application and trend of antibacterial drugs in Erdos Central Hospital from 2014 to 2016, and to promote the rational use and standardization of antibacterial drugs. Methods The use of antibacterial drugs amount, frequency of drug use (DDDs), daily drug cost (DDC), and management indicators of drugs in Erdos Central Hospital were analyzed, and the application status of antibacterial drugs were analyzed. Results Sales amount of antibacterial drug was increasing year by year from 2014 to 2016. The medication structure of antibacterial drugs was relatively stable, and the main use of the antibacterial drugs category was cephalosporins and fluoroquinolones. DDDs of carbapenems and antifungal drugs increased year by year, and DDDs of carbopenems increased most rapidly. DDC of most antibacterial drugs with top 10 DDDs was more than 100. The use intensity of antibacterial drugs (AUD) declined significantly over the past 3 years, from 48.45 DDD in 2014 to 40.20 DDD in 2016. Conclusion There are some problems in clinical application of antibacterial drugs in Erdos Central Hospital, suggesting that some measures should be taken to strengthen the evaluation of the drugs.