目的 探索茵膽平肝膠囊聯(lián)合多烯磷脂酰膽堿治療酒精性肝病的臨床療效。方法 選取2014年2月-2017年4月渭南市中心醫(yī)院收治的234例酒精性肝病患者，隨機(jī)分為對(duì)照組和治療組，每組各117例。對(duì)照組靜脈滴注多烯磷脂酰膽堿注射液，30 mL加入5%葡萄糖注射液250 mL，1次/d。治療組在對(duì)照組治療基礎(chǔ)上口服茵膽平肝膠囊，2粒/次，2次/d。兩組均連續(xù)治療30 d。觀察兩組患者的臨床療效，比較兩組治療前后天冬氨酸氨基轉(zhuǎn)移酶（AST）、丙氨酸氨基轉(zhuǎn)移酶（ALT）、總膽紅素（TBil）、堿性磷酸酶（ALP）的變化情況。結(jié)果 治療后，對(duì)照組和治療組的總有效率分別為80.34%、94.87%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組AST、ALT、TBil、ALP水平均顯著降低，同組治療前后差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，治療組AST、ALT、TBil、ALP水平顯著低于對(duì)照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。對(duì)照組和治療組的不良反應(yīng)發(fā)生率分別為28.2%、9.4%，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 茵膽平肝膠囊聯(lián)合多烯磷脂酰膽堿治療酒精性肝病具有顯著療效，能明顯改善患者肝功能，不良反應(yīng)較少，具有一定的臨床推廣應(yīng)用價(jià)值。

Objective To explore the clinical efficacy of Yindan Pinggan Capsules combined with polyene phosphatidylcholine in treatment of alcoholic liver disease. Methods Patients (234 cases) with alcoholic liver disease in Weinan Central Hospital from February 2014 to April 2017 were randomly divided into control (117 cases) and treatment (117 cases) groups. Patients in the control group were iv administered with Polyene Phosphatidylcholine Injection, 30 mL added into 5% glucose injection, once daily. Patients in the treatment group were po administered with Yindan Pinggan Capsules on the basis of the control group, 2 grains/time, twice daily. All patients were continuously treated for 30 d. After treatment, the clinical efficacy was evaluated, and the changes of AST, ALT, TBil, and ALP in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 80.34% and 94.87%, respectively, and there was difference between two groups (P<0.05). After treatment, AST, ALT, TBil, and ALP in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, AST, ALT, TBil, and ALP in the treatment group were lower than those in the control group, and there was difference between two groups (P<0.05). After treatment, the incidence of adverse reactions in the control and treatment groups were 28.2% and 9.4%, respectively, and there was difference between two groups (P<0.05). Conclusion Yindan Pinggan Capsules combined with polyene phosphatidylcholine has a significant effect in treatment of alcoholic liver disease, and can obviously improve the liver function of the patient with less adverse reaction, which has a certain clinical application value.