[關(guān)鍵詞]
[摘要]
目的 探究鼻淵糖漿聯(lián)合氯雷他定治療變應(yīng)性鼻炎的臨床效果。方法 選取2015年1月-2016年12月在江蘇省金湖縣人民醫(yī)院接受治療的變應(yīng)性鼻炎患者96例,隨機分為對照組和治療組,每組各48例。對照組患者口服氯雷他定分散片,10 mg/次,1次/d;治療組患者在對照組的基礎(chǔ)上口服鼻淵糖漿,15 mL/次,3次/d。兩組患者均治療3個月。觀察兩組患者臨床效果,比較兩組患者治療前后呼吸功能水平和癥狀體征評分以及復(fù)發(fā)情況。結(jié)果 治療后,對照組和治療組臨床總有效率分別為68.75%和89.58%,兩組比較差異具有統(tǒng)計學(xué)意義(P<0.05)。治療后,兩組患者最大呼氣流速(PEF)水平顯著提高,PEF變異率和癥狀體征評分顯著降低,同組比較差異具有統(tǒng)計學(xué)意義(P<0.05);且治療組患者上述評價指標(biāo)明顯好于對照組,兩組比較差異具有統(tǒng)計學(xué)意義(P<0.05)。治療后,治療組患者復(fù)發(fā)和反復(fù)情況遠(yuǎn)低于對照組患者,兩組比較差異具有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論 鼻淵糖漿聯(lián)合氯雷他定在迅速消除變應(yīng)性鼻炎病癥體征和減少病情反復(fù)方面效果顯著,具有一定的臨床推廣應(yīng)用價值。
[Key word]
[Abstract]
Objective To explore the clinical efficacy of Biyuan Syrup combined with loratadine in treatment of allergic rhinitis. Method Patients (96 cases) with allergic rhinitis in Jinhu County People's Hospital from January 2015 to December 2016 were randomly divided into control and treatment groups, and each group had 48 cases. Patients in the control group were po administered with Loratadine Dispersible Tablets, 10 mg/time, once daily. Patients in the treatment group were po administered with Biyuan Syrup on the basis of the control group, 15 mL/time, three times daily. Patients in two groups were treated for 3 months. After treatment, the clinical efficacy was evaluated, and respiratory function, symptom and sign scores, and recurrence in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 68.75% and 89.58%, respectively, and there were differences between two groups (P<0.05). After treatment, PEF levels in two groups were significantly increased, but PEF variation rate, and symptom and sign scores were significantly decreased, and there were differences in the same group (P<0.05). And these evaluation indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the recurrence rate in the treatment group was significantly lower than that in the control group, with significant difference between two groups (P<0.05). Conclusion Biyuan Syrup combined with loratadine has significant effect on eliminating the symptoms of allergic rhinitis and reducing the recurrence in treatment of allergic rhinitis, which has a certain clinical application value.
[中圖分類號]
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