目的 分析鄭州市骨科醫(yī)院口服非甾體抗炎藥（NSAIDs）的使用情況，為臨床合理用藥提供參考。方法 調(diào)取2014—2016年口服NSAIDs使用情況的相關(guān)信息，對銷售金額、用藥頻度（DDDs）、日均費(fèi)用（DDC）、藥品排序比（B/A）等指標(biāo)進(jìn)行統(tǒng)計(jì)和分析。結(jié)果 口服NSAIDs的銷售金額呈逐年上升趨勢，依托考昔片、醋氯芬酸緩釋片、塞來昔布膠囊和右旋酮洛芬氨丁三醇片的銷售金額排前4位；依托考昔片、醋氯芬酸緩釋片和塞來昔布膠囊的DDDs穩(wěn)居前3位；依托考昔片的DDC最高，阿司匹林腸溶片的DDC最低。2014—2016年各藥品的B/A值介于0.5～1.5的分別有11、11、10種，總體同步性很好。結(jié)論 2014—2016年鄭州市骨科醫(yī)院口服NSAIDs的應(yīng)用基本合理。

Objective To investigate the utilization of oral non-steroidal anti-inflammatory drugs (NSAIDs) in Zhengzhou Orthopaedic Hospital and provide reference for rational drug use in clinic. Methods Data of NSAIDs in 25 hospitals in Zhengzhou Orthopaedic Hospital from 2014 to 2016 were selected, and consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and sequence ratio (B/A) of NSAIDs were retrospectively analyzed. Results Consumption sum of oral NSAIDs showed a rising trend year by year, and the top four drugs were still Etoricoxib Tablets, Aceclofenac Sustained-release Tablets, Celecoxib Capsules, and Dexketoprofen Trometamol Tablets. DDDs of Etoricoxib Tablets, Aceclofenac Sustained-release Tablets, and Celecoxib Capsules ranked the top three. DDC of Imrecoxib Tablets ranked the first, while DDC of Aspirin Enteric-coated Tablets ranked the end. The number of drugs whose B/A values between 0.5 to 1.5 was 11, 11, and 10, respectively. The overall synchronization was good. Conclusion The application of oral NSAIDs is basically rational in Zhengzhou Orthopaedic Hospital from 2014 to 2016.