目的 探討接骨七厘片聯(lián)合鹿瓜多肽治療四肢骨折的臨床有效性與安全性。方法 選取2012年6月—2015年6月天津市第五中心醫(yī)院收治的四肢骨折患者82例，根據(jù)用藥方案不同分成對照組和治療組，每組各41例。對照組患者靜脈滴注注射用鹿瓜多肽，24 mg加入生理鹽水，1次/d；治療組患者在對照組基礎上口服接骨七厘片，5片/次，2次/d。兩組患者均連續(xù)治療8周。觀察兩組患者臨床療效，比較治療前后兩組患者四肢骨折愈合時間、視覺模擬評分（VAS）評分和SF-36評分。結果 治療后，對照組臨床總有效率為78.05%，顯著低于治療組的95.12%，兩組比較差異具有統(tǒng)計學意義（P<0.05）。治療后，治療組患者脛骨干、尺橈骨、股骨干、肱骨干骨折愈合時間均明顯短于對照組患者，兩組比較差異具有統(tǒng)計學意義（P<0.05）。治療后，兩組患者VAS評分顯著降低，SF-36評分顯著升高，同組比較差異具有統(tǒng)計學意義（P<0.05）；且治療組患者VAS評分和SF-36評分改善情況明顯優(yōu)于對照組（P<0.05）。結論 接骨七厘片聯(lián)合鹿瓜多肽治療四肢骨折可顯著提升患者的臨床有效率，改善患者的疼痛癥狀與生活質量。

objective To explore the clinical efficacy and safety of Jiegu Qili Tables combined with cervus and cucumis polypeptide in treatment of limbs fracture. Methods Patients (82 cases) with limbs fracture in Tianjin Fifth Central Hospital from June 2012 to June 2015 were divided into control and treatment groups according to different treatments, and each had 41 cases. Patients in the control group were iv administered with Cervus and Cucumis Polypeptide for injection, 24 mg added into normal saline, once daily. Patients in the treatment group were po administered with Jiegu Qili Tables on the basis of the control group, 5 tables/time, twice daily. Patients in two groups were treated for 8 weeks. After treatment, the clinical efficacy was evaluated, and the healing time of fracture of limbs, VAS scores, and SF-36 scores in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 78.05%, which was significantly lower than 95.12% in the treatment group, and there were differences between two groups (P < 0.05). After treatment, the healing time of fracture of tibial diaphysis, ulnar and radial bone, femoral shaft, and humeral diaphysis in the treatment group were obviously shorter than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the VAS scores in two groups were significantly decreased, but the SF-36 scores were significantly increased, and the difference was statistically significant in the same group (P < 0.05). And the improvement of VAS and SF-36 scores in the treatment group were significantly better than that in the control group (P < 0.05). Conclusion Jiegu Qili Tables combined with cervus and cucumis polypeptide can improve the clinical efficiency in treatment of limbs fracture, and improve the pain symptoms and quality of life.