目的 分析2013—2016年天津市津南區(qū)咸水沽醫(yī)院第二類精神藥品的使用情況和變化趨勢(shì)，為促進(jìn)臨床合理用藥提供依據(jù)。方法 對(duì)2013—2016年天津市津南區(qū)咸水沽醫(yī)院第二類精神藥品的銷售量、銷售金額、用藥頻度（DDDs）、日均藥費(fèi)（DDC）、藥品排序比（B/A）進(jìn)行統(tǒng)計(jì)和分析。結(jié)果 2013—2016年，第二類精神藥品的銷售金額逐年增長(zhǎng)，地佐辛注射液、咪達(dá)唑侖注射液的銷售金額排名始終居前2位。第二類精神藥物的DDDs逐年增長(zhǎng)，艾司唑侖片、地西泮片的DDDs始終居前3位。各類精神藥品的DDC排名基本穩(wěn)定。地佐辛注射液、咪達(dá)唑侖注射液的DDC值較大，位居前兩位。曲馬多注射液、鹽酸曲馬多緩釋片、酒石酸唑吡坦片、地西泮注射液、苯巴比妥鈉注射液、阿普唑侖片的B/A接近1.00，但個(gè)別精神藥品的B/A大于1.00。結(jié)論 天津市津南區(qū)咸水沽醫(yī)院第二類精神藥品的使用基本合理，但個(gè)別藥品存在不合理現(xiàn)象。

objective To investigate the usage and variation tendency of second class psychotropic substances in Jinnan Xianshuigu Hospital of Tianjin City from 2013 to 2016, in order to provide reference for rational drug use in clinic. Methods The utilization, consumption sums, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) of second class psychotropic substances in Tianjin Xianshuigu Hospital from 2013 to 2016 were calculated and analyzed. Results Consumption sums of second class psychotropic substances increased year by year from 2013 to 2016. Consumption sums of Dezocine Injection and Midazolam Injection always ranked the top two. DDDs of the second class of psychotropic drugs increased year by year, and DDDs of Escitalizine Tablets and Diazepam Tablets always ranked the top three. DDC rankings of the second class of psychotropic drugs were stable. DDC of Dezocine Injection and Midazolam Injection were larger, and ranked the top two. B/A of Tramadol Injection, Tramadol Hydrochloride Sustained Release Tablets, Zolpidem Tartrate Tablets, Diazepam Injection, Phenobarbitol Sodium Injection, and Alprazolam Tablets were close to 1.00. While B/A of individual psychotropic drugs was far larger than 1.00. Conclusion The use of the second class of psychotropic drugs in Jinnan Xianshuigu Hospital of Tianjin City is basically reasonable, but there are still some unreasonable use.