[關(guān)鍵詞]
[摘要]
目的 探討桉檸蒎腸溶軟膠囊聯(lián)合頭孢克肟治療老年肺炎的臨床療效。方法 選取2017年2月-2017年9月在航空總醫(yī)院治療的老年肺炎患者82例,根據(jù)用藥的差別分為對照組(41例)和治療組(41例)。對照組口服頭孢克肟膠囊,0.1 g/次,2次/d;治療組在對照組基礎(chǔ)上口服桉檸蒎腸溶軟膠囊,0.3 g/次,3次/d。兩組患者均經(jīng)過14 d治療。觀察兩組患者臨床療效,比較治療前后兩組患者臨床癥狀評分和血清學指標。結(jié)果 治療后,對照組和治療組的臨床有效率分別為80.49%和97.56%,兩組比較差異具有統(tǒng)計學意義(P<0.05)。治療后,兩組患者咳嗽、咳痰、發(fā)熱、喘息氣急評分均顯著降低,同組比較差異具有統(tǒng)計學意義(P<0.05);且治療組患者的臨床癥狀評分明顯低于對照組,兩組比較差異具有統(tǒng)計學意義(P<0.05)。治療后,兩組患者血清C反應(yīng)蛋白(CRP)、降鈣素(PCT)和白細胞介素-6(IL-6)水平均顯著降低,同組比較差異具有統(tǒng)計學意義(P<0.05);且治療組血清學指標比對照組降低更顯著,兩組比較差異具有統(tǒng)計學意義(P<0.05)。結(jié)論 桉檸蒎聯(lián)合頭孢克肟膠囊治療老年肺炎可有效改善患者臨床癥狀,降低血清CRP、PCT和IL-6水平,具有一定的臨床推廣應(yīng)用價值。
[Key word]
[Abstract]
Objective To evaluate the clinical efficacy of Eucalyptol,Limonene and Pinene Enteric Soft Capsules combined with cefixime in treatment of senile pneumonia.Methods Patients (82 cases) with pneumonia in General Hospital of China Aviation from February 2017 to September 2017 were divided into control (41 cases) and treatment (41 cases) groups based on different treatment.Patients in the control group were po administered with Cefixime Capsules,0.1 g/time,twice daily.Patients in the treatment group were po administered with Eucalyptol,Limonene and Pinene Enteric Soft Capsules on the basis of the control group,0.3 g/time,three times daily.Patients in two groups were treated for 14 d.After treatment,the clinical efficacy was evaluated,and the clinical symptom scores,the serological indexes in two groups before and after treatment were compared.Results After treatment,the clinical efficacy in the control and treatment groups were 80.49% and 97.56%,respectively,and there were differences between two groups (P<0.05).After treatment,the cough,expectoration,fever,wheezing and shortness of breath scores in two groups was significantly decreased,and the difference was statistically significant in the same group (P<0.05).And these clinical symptom scores in the treatment group were significantly lower than those in the control group,with significant difference between two groups (P<0.05).After treatment,the serum CRP,PCT,but IL-6 levels in two groups were significantly decreased,and there were differences in the same group (P<0.05).And the serological indexes levels in the treatment group were significantly lower than those in the control group,with significant difference between two groups (P<0.05).Conclusion Eucalyptol,Limonene and Pinene Enteric Soft Capsules combined with cefixime in treatment of senile pneumonia can effectively improve the clinical symptoms and reduce the serum CRP,PCT,IL-6 levels,which has a certain clinical application value.
[中圖分類號]
[基金項目]