目的 探究調(diào)經(jīng)促孕丸聯(lián)合枸櫞酸氯米芬膠囊治療肥胖型多囊卵巢綜合征不孕的臨床療效。方法 選取2014年6月-2017年3月到商南縣中醫(yī)醫(yī)院接受治療的肥胖型多囊卵巢綜合癥患者102例為研究對象，按隨機(jī)數(shù)表法分為對照組和治療組，每組各51例。對照組從月經(jīng)周期第5天開始口服枸櫞酸氯米芬膠囊，50 mg/次，1次/d。治療組在對照組的基礎(chǔ)上從月經(jīng)周期第5天開始口服調(diào)經(jīng)促孕丸，5 g/次，2次/d。1個月為1個療程，兩組患者均連續(xù)治療3個療程。觀察和比較兩組的排卵率、妊娠率、妊娠早期流產(chǎn)率、激素水平和子宮內(nèi)膜厚度。結(jié)果 治療后，對照組和治療組排卵率分別為71%、92%，妊娠率分別為69%、91%，妊娠早期流產(chǎn)率分別為10%、2%，兩組排卵率、妊娠率、妊娠早期流產(chǎn)率比較差異具有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組卵泡刺激素（FSH）、黃體生成激素（LH）、LH/FSH水平均顯著降低，同組治療前后比較差異具有統(tǒng)計學(xué)意義（P<0.05）；且治療組這些激素水平明顯低于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。治療后，兩組子宮內(nèi)膜厚度均顯著減少，同組治療前后比較差異具有統(tǒng)計學(xué)意義（P<0.05）；且治療組子宮內(nèi)膜厚度明顯小于對照組，兩組比較差異具有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 調(diào)經(jīng)促孕丸聯(lián)合枸櫞酸氯米芬膠囊治療肥胖型多囊卵巢綜合征不孕具有較好的臨床療效，能降低FSH、LH水平，改善子宮內(nèi)膜厚度，提高排卵率和妊娠率，降低妊娠早期流產(chǎn)率，具有一定的臨床推廣應(yīng)用價值。

Objective To investigate the clinical effect of Tiaojing Cuyun Pills combined with Clomifene Citrate Capsules in treatment of obesity polycystic ovarian syndrome infertility. Methods Patients (102 cases) with obesity polycystic ovarian syndrome infertility in Shangnan County Chinese Medicine Hospital from June 2014 to March 2017 were randomly divided into control and treatment groups, and each group had 51 cases. Patients in the control group were po administered with Clomifene Citrate Capsules from the fifth day of menstrual cycle, 50 mg/time, once daily. Patients in the treatment group were po administered with Tiaojing Cuyun Pills on the basis of the control group, 5 g/time, twice daily. One month was 1 course, and patients in two groups were treated for 3 courses. After treatment, the ovulation rate, pregnancy rate, early pregnancy abortion rate, hormone level, and endometrial thickness in two groups were compared. Results After treatment, the ovulation rate in the control and treatment groups were 71% and 92%, respectively; the oviposit rates in the control and treatment groups were 69% and 91%, respectively, and the early pregnancy abortion rates in the control and treatment groups were 10% and 2%, respectively, and there was difference between two groups (P < 0.05). After treatment, the levels of FSH, LH, and LH/FSH in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the hormone levels in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the endometrial thicknesses in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the endometrial thickness >in the treatment group was significantly thicker than that in the control group, with significant difference between two groups (P < 0.05). Conclusion Tiaojing Cuyun Pills combined with Clomifene Citrate Capsules has clinical curative effect in treatment of obesity polycystic ovarian syndrome infertility, can decrease the levels of FSH and LH, improve the endometrial thickness, increase the ovulation rate and pregnancy rate, reduce the early pregnancy abortion rate, which has a certain clinical application value.